ReviewInternational journal of molecular sciences2023
Relative Humidity and Its Impact on the Immune System and Infections.
Review in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
46 citing papers in PubMed, 2 syntheses or guidelines pooled it, 122 citations in OpenAlex.
- Association of meteorological factors with allergic rhinitis: a systematic review and meta-analysis.BMC public health · 2025Pooled it
- Association of humidity and precipitation with asthma: a systematic review and meta-analysis.Frontiers in allergy · 2024Pooled it
- Long-Term Validation of a Consumer- vs. Industrial-Grade Indoor Radon and Air Quality Monitor at a School in Utah.Sensors (Basel, Switzerland) · 2026Article
- Analysis of Spatiotemporal Risks of Environmental Driving Factors of Respiratory Diseases.GeoHealth · 2026Article
- High humidity reprograms the gut mycobiome to promotemSystems · 2026Article
- Sex Differences in the Effects of High Temperature on Cardiovascular Disease Hospitalizations in Montreal.CJC open · 2026Article
- A theoretical index for understanding distinct land relative humidity trends in observations, reanalyses, and models.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- Article
- Environmental Determinants of Surgical Site Infections in Abdominal Surgeries: A Scoping Review of Evidence from East Africa.Journal of multidisciplinary healthcare · 2026Review
- Article
- Age-stratified respiratory viral detection patterns and exploratory environmental associations in a tertiary-care hospital testing cohort in Istanbul, Türkiye.Frontiers in microbiology · 2026Article
- Interaction effects of environmental factors with white blood cell profiles on mycobacterial pulmonary diseases: a case-control study.BMC infectious diseases · 2025Article
- Pathological characteristics of traditional Chinese medicine Shi Zheng and related therapeutic formula, effective compounds: a general review.Chinese medicine · 2025Review
- Integrated risks from air pollution and climate extremes: synergistic effects of ozone, heat, and humidity on cardiovascular mortality.BMC medicine · 2025Article
- Adverse Reactions to CT Contrast Agents: A 10-Year Study of Clinical and Environmental Risk Factors.Diagnostics (Basel, Switzerland) · 2025Article
- Age, sex and seasonal differences in COVID-19 viral load: a Lebanese cross-sectional study.BMC infectious diseases · 2025Article
- How do climate conditions and urbanisation impact nontuberculous mycobacterial infections? An Italian nationwide case-control study.ERJ open research · 2025Article
- Improving disinfection and packaging strategies for the effective preservation of welsh onion (Allium fistulosum L.).Scientific reports · 2025Article
- Genetic Susceptibility to Tuberculosis and the Utility of Polygenic Scores in Population Stratification.International journal of molecular sciences · 2025Review
- Effects of one year of extreme isolation in Antarctica on olfactory and gustatory functions.Scientific reports · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Relative humidity (RH) represents an underestimated outdoor and indoor environmental parameter. Conditions below and above the optimal range could facilitate infectious transmission as well as the exacerbation of respiratory diseases. The aim of this review is to outline the consequences for health of suboptimal RH in the environment and how to limit this negative impact. RH primarily affects the rheological properties of the mucus, modifying its osmolarity and thus the mucociliary clearance. The integrity of the physical barrier, maintained by mucus and tight junctions, is critical for protection from pathogens or irritants. Moreover, the control of RH seems to be a strategy to prevent and control the spread of viruses and bacteria. However, the imbalance of RH in the outdoor and indoor environments is frequently associated with the presence of other irritants, allergens, and pathogens, and therefore the burden of a single risk factor is not clearly defined in different situations. Nonetheless, RHmay have a synergistic negative effect with these risk factors, and its normalization, if possible, may have a positive impact on a healthier environment.
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Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.