Evidence map›Paper›PMID 37298222›Full record

ArticleInternational journal of molecular sciences2023

Exercise Training Attenuates Acute β-Adrenergic Receptor Activation-Induced Cardiac Inflammation via the Activation of AMP-Activated Protein Kinase.

Mi Zhang, Akehu Alemasi, Mingming Zhao, Wenli Xu, Youyi Zhang, Wei Gao, Haiyi Yu, Han Xiao

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 10 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Review
  5. Review
  6. Review
  7. Review
  8. Article
  9. Heart failure, inflammation and exercise.International journal of biological sciences · 2025
    Review
  10. Review
  11. Review
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Mi ZhangDepartment of Cardiology and Institute of Vascular Medicine, Peking University Third Hospital, Beijing 100191, China.
Akehu AlemasiDepartment of Cardiology and Institute of Vascular Medicine, Peking University Third Hospital, Beijing 100191, China.
Mingming ZhaoDepartment of Cardiology and Institute of Vascular Medicine, Peking University Third Hospital, Beijing 100191, China.
Wenli XuDepartment of Cardiology and Institute of Vascular Medicine, Peking University Third Hospital, Beijing 100191, China.
Youyi ZhangDepartment of Cardiology and Institute of Vascular Medicine, Peking University Third Hospital, Beijing 100191, China.
Wei GaoDepartment of Cardiology and Institute of Vascular Medicine, Peking University Third Hospital, Beijing 100191, China.
Haiyi YuDepartment of Cardiology and Institute of Vascular Medicine, Peking University Third Hospital, Beijing 100191, China.ORCID 0000-0003-0761-5270
Han XiaoDepartment of Cardiology and Institute of Vascular Medicine, Peking University Third Hospital, Beijing 100191, China.ORCID 0000-0003-4124-9411
Chinese Academy of Medical Sciences & Peking Union Medical College · CNPeking University · CN

Funding

Beijing Natural Science Foundation No. 7212125CAMS Innovation Fund for Medical Sciences No. 2021-I2M-5-003Key Clinical Projects of Peking University Third Hospital BYSYZD2019022National Key R&D Program 2021YFF0501401, 2020YFA0803800Natural Science Foundation of China 82030072, 81830009, 81871850, 81972149
6 · The paper itself

Abstract

Exercise has proven cardiac benefits, but the underlying mechanisms of exercise that protect the heart from acute sympathetic stress injuries remain unknown. In this study, adult C57BL/6J mice and their AMP-activated protein kinase α2 knockout (AMPKα2

Indexed as

AMP-Activated Protein KinasesReceptors, Adrenergic, betaAdrenergic beta-AgonistsAnimalsArrhythmias, CardiacExerciseInflammasomesInflammationIsoproterenolMiceMice, Inbred C57BLMyocytes, CardiacNLR Family, Pyrin Domain-Containing 3 ProteinReactive Oxygen SpeciesAdrenergic beta-AgonistsAMP-Activated Protein KinasesInflammasomesIsoproterenolNLR Family, Pyrin Domain-Containing 3 ProteinReactive Oxygen SpeciesReceptors, Adrenergic, betaacute sympathetic stressAMP-activated protein kinaseexercise trainingNLR family, pyrin domain-containing 3

Identifiers

PMID37298222
PMCPMC10252890
OpenAlexW4378470855

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.