Evidence map›Paper›PMID 37298207›Full record

ArticleInternational journal of molecular sciences2023

Effects of Cobra Cardiotoxins on Intracellular Calcium and the Contracture of Rat Cardiomyocytes Depend on Their Structural Types.

Alexey S Averin, Alexey V Berezhnov, Oleg Y Pimenov, Miliausha H Galimova, Vladislav G Starkov, Victor I Tsetlin, Yuri N Utkin

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.9field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Review
  3. Identification and analgesic activity study of analgesic protein Ⅶ-2 fromThe journal of venomous animals and toxins including tropical diseases · 2024
    Article
  4. Molecular Mechanisms of Animal Toxins, Venoms and Antivenoms.International journal of molecular sciences · 2023
    Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Alexey S AverinInstitute of Cell Biophysics, Federal Research Center "Pushchino Scientific Center of Biological Research", Pushchino Branch, Russian Academy of Sciences, Pushchino 142290, Russia.
Alexey V BerezhnovInstitute of Cell Biophysics, Federal Research Center "Pushchino Scientific Center of Biological Research", Pushchino Branch, Russian Academy of Sciences, Pushchino 142290, Russia.ORCID 0000-0003-0271-6179
Oleg Y PimenovInstitute of Theoretical and Experimental Biophysics, Russian Academy of Sciences, Pushchino 142290, Russia.
Miliausha H GalimovaInstitute of Theoretical and Experimental Biophysics, Russian Academy of Sciences, Pushchino 142290, Russia.
Vladislav G StarkovShemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Moscow 117997, Russia.
Victor I TsetlinShemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Moscow 117997, Russia.ORCID 0000-0002-7980-6191
Yuri N UtkinShemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Moscow 117997, Russia.ORCID 0000-0002-4609-970X
Institute of Bioorganic Chemistry · RUInstitute of Cell Biophysics · RUInstitute of Theoretical and Experimental Biophysics · RU

Funding

Russian Science Foundation 21-14-00316
6 · The paper itself

Abstract

Cardiotoxins (CaTx) of the three-finger toxin family are one of the main components of cobra venoms. Depending on the structure of the N-terminal or the central polypeptide loop, they are classified into either group I and II or P- and S-types, respectively, and toxins of different groups or types interact with lipid membranes variably. While their main target in the organism is the cardiovascular system, there is no data on the effects of CaTxs from different groups or types on cardiomyocytes. To evaluate these effects, a fluorescence measurement of intracellular Ca

Indexed as

Cobra Cardiotoxin ProteinsContractureToxins, BiologicalAnimalsCalciumCalcium, DietaryElapid VenomsMyocytes, CardiacPeptidesRatsCalciumCalcium, DietaryCobra Cardiotoxin ProteinsElapid VenomsPeptidesToxins, Biologicalcalcium concentrationcardiomyocytecardiotoxinhypercontracture

Identifiers

PMID37298207
PMCPMC10253216
OpenAlexW4378379377

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.