Evidence map›Paper›PMID 37298095›Full record

ReviewInternational journal of molecular sciences2023

The Essential Role of microRNAs in Inflammatory and Autoimmune Skin Diseases-A Review.

Klaudia Dopytalska, Anna Czaplicka, Elżbieta Szymańska, Irena Walecka

Open access · goldAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
9.1field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 32 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Article
  5. Article
  6. Review
  7. Review
  8. Article
  9. Review
  10. Review
  11. Epigenetic Modifications in Vitiligo.Clinical reviews in allergy & immunology · 2025
    Review
  12. Interpreting the Function of the IL-23/IL-17 Axis through Bioinformatics.Endocrine, metabolic & immune disorders drug targets · 2025
    Review
  13. Review
  14. Identification and Validation of Hub Genes in Hidradenitis Suppurativa.Clinical, cosmetic and investigational dermatology · 2025
    Article
  15. Review
  16. Review
  17. Article
  18. Review
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Klaudia DopytalskaDepartment of Dermatology, Centre of Postgraduate Medical Education, 02-507 Warsaw, Poland.ORCID 0000-0002-3692-2635
Anna CzaplickaDepartment of Dermatology, Centre of Postgraduate Medical Education, 02-507 Warsaw, Poland.
Elżbieta SzymańskaDepartment of Dermatology, Centre of Postgraduate Medical Education, 02-507 Warsaw, Poland.
Irena WaleckaDepartment of Dermatology, Centre of Postgraduate Medical Education, 02-507 Warsaw, Poland.
Postgraduate School of Molecular Medicine · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The etiopathogenesis of autoimmune skin diseases is complex and still not fully understood. The role of epigenetic factors is emphasized in the development of such diseases. MicroRNAs (miRNAs), a group of non-coding RNAs (ncRNAs-non-coding RNAs), are one of the important post-transcriptional epigenetic factors. miRNAs have a significant role in the regulation of the immune response by participating in the process of the differentiation and activation of B and T lymphocytes, macrophages, and dendritic cells. Recent advances in research on epigenetic factors have provided new insights into the pathogenesis and potential diagnostic and therapeutic targets of many pathologies. Numerous studies revealed a change in the expression of some microRNAs in inflammatory skin disorders, and the regulation of miRNA expression is a promising therapeutic goal. This review presents the state of the art regarding changes in the expression and role of miRNAs in inflammatory and autoimmune skin diseases, including psoriasis, atopic dermatitis, vitiligo, lichen planus, hidradenitis suppurativa, and autoimmune blistering diseases.

Indexed as

Autoimmune DiseasesDermatitis, AtopicHidradenitis SuppurativaMicroRNAsPsoriasisHumansSkinMicroRNAsatopic dermatitisautoimmune blistering diseasesautoimmune diseasehidradenitis suppurativalichen planusmicroRNApsoriasisskin diseasevitiligo

Identifiers

PMID37298095
PMCPMC10253000
OpenAlexW4378083509

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.