Evidence map›Paper›PMID 37298031›Full record

ArticleJournal of clinical medicine2023

Evaluation of Ocular Perfusion in Patients with End-Stage Renal Disease Receiving Hemodialysis Using Optical Coherence Tomography Angiography.

Larissa Lahme, Jens Julian Storp, Elena Marchiori, Eliane Esser, Nicole Eter, Natasa Mihailovic, Maged Alnawaiseh

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
2.8field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 10 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Larissa LahmeDepartment of Ophthalmology, University of Muenster Medical Center, 48149 Muenster, Germany.
Jens Julian StorpDepartment of Ophthalmology, University of Muenster Medical Center, 48149 Muenster, Germany.ORCID 0000-0002-8063-6548
Elena MarchioriDepartment of Vascular and Endovascular Surgery, University of Muenster Medical Center, 48149 Muenster, Germany.ORCID 0000-0003-2643-2621
Eliane EsserDepartment of Ophthalmology, University of Muenster Medical Center, 48149 Muenster, Germany.
Nicole EterDepartment of Ophthalmology, University of Muenster Medical Center, 48149 Muenster, Germany.
Natasa MihailovicDepartment of Ophthalmology, Klinikum Bielefeld gem. GmbH, 33604 Bielefeld, Germany.
Maged AlnawaisehDepartment of Ophthalmology, Klinikum Bielefeld gem. GmbH, 33604 Bielefeld, Germany.
Klinikum Bielefeld · DEUniversity of Münster · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hemodialysis (HD) is known to affect ocular blood flow. This case-control study aims to evaluate macular and peripapillary vasculature in patients with end-stage renal disease (ESRD) receiving HD in comparison to matched controls. A total of 24 eyes of 24 ESRD patients receiving HD and 24 eyes of 24 healthy, age- and gender-matched control subjects were prospectively included in this study. Optical coherence tomography angiography was used to image the superficial (SCP), deep (DCP), and choriocapillary (CC) macular vascular plexus, as well as the radial peripapillary capillaries (RPC) of the optic disc. In addition, retinal thickness (RT) and retinal volume (RV) were compared between both groups. Flow density (FD) values of each retinal layer and data of parameters related to the foveal avascular zone (FAZ), as well as RT and RV, were analyzed using Mann-Whitney U tests. There was no significant difference in FAZ parameters between the two groups. Whole en face FD of the SCP and CC was noticeably reduced in the HD group in comparison to the control group. FD was negatively correlated with the duration of HD treatment. RT and RV were significantly smaller in the study group than in controls. Retinal microcirculation appears altered in patients with ESRD undergoing HD. Concurrently, the DCP appears more resilient towards hemodynamic changes in comparison to the other microvascular retinal layers. OCTA is a useful, non-invasive tool to investigate retinal microcirculation in ESRD patients.

Indexed as

flow densityfoveal avascular zonemacular perfusionoptic nerverenal diseasevessel density

Identifiers

PMID37298031
PMCPMC10253578
OpenAlexW4379473709

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.