ArticleJournal of clinical medicine2023
Glucose Levels of the Oral Glucose Tolerance Test (oGTT) Can Predict Adverse Pregnancy Outcomes in Women with Gestational Diabetes (GDM).
Article in Journal of clinical medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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14 citing papers in PubMed, 17 citations in OpenAlex.
- Maternal and neonatal outcomes among Chinese women meeting NICE but not IADPSG criteria for gestational diabetes mellitus: A retrospective cohort study.Journal of biomedical research · 2026Article
- Development and validation of gestational diabetes dietary psychological evaluation scale.BMC pregnancy and childbirth · 2025Article
- Gestational diabetes mellitus subtypes: from one-size-fits-all to precision medicine.Hormones (Athens, Greece) · 2025Review
- Article
- Gestational diabetes mellitus subtypes according to oral glucose tolerance test and pregnancy outcomes.Endocrine · 2025Article
- The flat glucose response curve during oral glucose tolerance tests in Chinese pregnant women and its association with adverse outcomes.Acta obstetricia et gynecologica Scandinavica · 2025Article
- The Molecular Mechanism of Craniofacial Cartilage Deformity Induced by High Glucose in Zebrafish.Current issues in molecular biology · 2025Article
- Effect of Initial Glucose Tolerance Test Response on Pregnancy Outcomes in Type A1 Gestational Diabetes.Medical science monitor : international medical journal of experimental and clinical research · 2025Article
- Association between area under the curve of oral glucose tolerance test and the risk of preterm birth among women with gestational diabetes mellitus: a mediation effect of gestational weight gain.BMC pregnancy and childbirth · 2025Article
- History of large-for-gestational-age birth is independently associated with subsequent gestational diabetes in Chinese multiparous women: a retrospective cohort study.Frontiers in endocrinology · 2025Article
- Ethnic-specific oral glucose tolerance (OGTT) phenotypes in women with hyperglycemia in pregnancy.BMJ open diabetes research & care · 2024Article
- Post-load glucose is a stronger predictor of adverse pregnancy outcomes than first-trimester HbA1c in women without gestational diabetes.Journal of diabetes investigation · 2024Article
- Dietary Intake and Oral Glucose Tolerance Test Results in Women with Gestational Diabetes.Journal of clinical medicine · 2024Article
- The CHANGED Score-A New Tool for the Prediction of Insulin Dependency in Gestational Diabetes.Journal of clinical medicine · 2023Article
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6 authors at 1 institution in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
OBJECTIVES AND
backgroundGestational diabetes (GDM) is a common pregnancy complication defined as a glucose intolerance diagnosis during pregnancy. GDM is strongly associated with adverse fetal and maternal outcomes. In Germany, to screen and diagnose GDM we use a 1 h 50 g oGCT (oral glucose challenge test) followed by a 2 h 75 g oGTT if the first was pathological. This analysis examines the correlation of 75 g oGTT glucose levels and fetomaternal outcome.
methodsData from 1664 patients from a gestational diabetes consultation clinic at the Charité University Hospital in Berlin, Germany, were analyzed retrospectively from 2015 to 2022. The 75 g oGTT blood glucose levels were categorized into isolated fasting hyperglycemia (GDM-IFH), isolated post-load hyperglycemia (GDM-IPH) and combined hyperglycemia (GDM-CH), using the levels of the fasting, 1 h and 2 h values, after glucose application. These subtypes were compared based on their baseline characteristics as well as fetal and maternal outcome.
resultsGDM-IFH and GDM-CH women displayed higher pre-conceptional BMI and required insulin therapy more frequently (
conclusionThis analysis shows a strong association between the glucose response pattern in the 75 g oGTT and adverse perinatal fetomaternal outcome. The differences among the subgroups, specifically concerning insulin therapy, mode of delivery and fetal growth, suggest an individualized approach to prenatal care after a GDM diagnosis.
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