Evidence map›Paper›PMID 37297898›Full record

ArticleJournal of clinical medicine2023

The Association between Dysnatraemia during Hospitalisation and Post-COVID-19 Mental Fatigue.

Gerardo Salvato, Elvira Inglese, Teresa Fazia, Francesco Crottini, Daniele Crotti, Federica Valentini, Giulio Palmas, Alessandra Bollani, Stefania Basilico, Martina Gandola and 7 more

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 4 institutions in 1 country.

Gerardo SalvatoDepartment of Brain and Behavioral Sciences, University of Pavia, 27100 Pavia, Italy.ORCID 0000-0003-2921-8858
Elvira IngleseDepartment of Brain and Behavioral Sciences, University of Pavia, 27100 Pavia, Italy.ORCID 0000-0002-8856-3558
Teresa FaziaDepartment of Brain and Behavioral Sciences, University of Pavia, 27100 Pavia, Italy.
Francesco CrottiniDepartment of Brain and Behavioral Sciences, University of Pavia, 27100 Pavia, Italy.
Daniele CrottiDepartment of Brain and Behavioral Sciences, University of Pavia, 27100 Pavia, Italy.
Federica ValentiniCognitive Neuropsychology Centre, ASST "Grande Ospedale Metropolitano" Niguarda, 20162 Milan, Italy.
Giulio PalmasCognitive Neuropsychology Centre, ASST "Grande Ospedale Metropolitano" Niguarda, 20162 Milan, Italy.
Alessandra BollaniCognitive Neuropsychology Centre, ASST "Grande Ospedale Metropolitano" Niguarda, 20162 Milan, Italy.
Stefania BasilicoCognitive Neuropsychology Centre, ASST "Grande Ospedale Metropolitano" Niguarda, 20162 Milan, Italy.
Martina GandolaDepartment of Brain and Behavioral Sciences, University of Pavia, 27100 Pavia, Italy.ORCID 0000-0002-0537-586X
Giorgio GelosaNeuroMI, Milan Centre for Neuroscience, 20126 Milan, Italy.
Davide GentiliniDepartment of Brain and Behavioral Sciences, University of Pavia, 27100 Pavia, Italy.
Luisa BernardinelliDepartment of Brain and Behavioral Sciences, University of Pavia, 27100 Pavia, Italy.ORCID 0000-0002-7551-6664
Andrea StracciariDepartment of Psychology, University of Bologna, 40126 Bologna, Italy.
Francesco ScaglioneDepartment of Laboratory Medicine, ASST "Grande Ospedale Metropolitano" Niguarda, 20162 Milan, Italy.
Elio Clemente AgostoniNeuroMI, Milan Centre for Neuroscience, 20126 Milan, Italy.
Gabriella BottiniDepartment of Brain and Behavioral Sciences, University of Pavia, 27100 Pavia, Italy.
University of Pavia · ITAzienda Socio Sanitaria Territoriale Grande Ospedale Metropolitano Niguarda · ITUniversity of Bologna · ITUniversity of Milan · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

COVID-19 may induce short- and long-term cognitive failures after recovery, but the underlying risk factors are still controversial. Here, we investigated whether (i) the odds of experiencing persistent cognitive failures differ based on the patients' disease course severity and sex at birth; and (ii) the patients' electrolytic profile in the acute stage represents a risk factor for persistent cognitive failures. We analysed data from 204 patients suffering from COVID-19 and hospitalised during the first pandemic wave. According to the 7-point WHO-OS scale, their disease course was classified as severe or mild. We investigated the presence of persistent cognitive failures collected after hospital discharge, while electrolyte profiles were collected during hospitalisation. The results showed that females who suffered from a mild course compared to a severe course of COVID-19 had a higher risk of presenting with persistent mental fatigue after recovery. Furthermore, in females who suffered from a mild course of COVID-19, persistent mental fatigue was related to electrolyte imbalance, in terms of both hypo- and hypernatremia, during hospitalisation in the acute phase. These findings have important implications for the clinical management of hospitalised COVID-19 patients. Attention should be paid to potential electrolyte imbalances, mainly in females suffering from mild COVID-19.

Indexed as

dysnatraemiaelectrolyte imbalancelong COVID-19mental fatigue

Identifiers

PMID37297898
PMCPMC10253452
OpenAlexW4378528296

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.