Evidence map›Paper›PMID 37297803›Full record

ReviewJournal of clinical medicine2023

Prenatal Diagnosis of an Intrathoracic Left Kidney Associated with Congenital Diaphragmatic Hernia: Case Report and Systematic Review.

Giuliana Orlandi, Paolo Toscano, Olimpia Gabrielli, Enrica Di Lella, Antonia Lettieri, Luigi Manzo, Laura Letizia Mazzarelli, Carmine Sica, Letizia Di Meglio, Lavinia Di Meglio and 5 more

Open access · goldAbstract readReview
In one paragraph

Review in Journal of clinical medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
4.4field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 14 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 5 institutions in 1 country.

Giuliana OrlandiDepartment of Neuroscience, Reproductive Sciences and Dentistry, School of Medicine, University of Naples Federico II, 80131 Naples, Italy.ORCID 0000-0001-9177-8552
Paolo ToscanoDepartment of Neuroscience, Reproductive Sciences and Dentistry, School of Medicine, University of Naples Federico II, 80131 Naples, Italy.
Olimpia GabrielliDepartment of Neuroscience, Reproductive Sciences and Dentistry, School of Medicine, University of Naples Federico II, 80131 Naples, Italy.ORCID 0000-0002-6151-0683
Enrica Di LellaDepartment of Neuroscience, Reproductive Sciences and Dentistry, School of Medicine, University of Naples Federico II, 80131 Naples, Italy.
Antonia LettieriDiagnostica Ecografica e Prenatale di A. Di Meglio, 80133 Naples, Italy.
Luigi ManzoDepartment of Neuroscience, Reproductive Sciences and Dentistry, School of Medicine, University of Naples Federico II, 80131 Naples, Italy.
Laura Letizia MazzarelliDepartment of Neuroscience, Reproductive Sciences and Dentistry, School of Medicine, University of Naples Federico II, 80131 Naples, Italy.
Carmine SicaDiagnostica Ecografica e Prenatale di A. Di Meglio, 80133 Naples, Italy.
Letizia Di MeglioRadiology Department, School of Medicine, University of Milan, 20133 Milan, Italy.ORCID 0000-0002-6494-986X
Lavinia Di MeglioPediatric Department, Bambino Gesù Children's Research Hospital IRCCS, 00165 Rome, Italy.
Ferdinando Antonio GulinoDepartment of Obstetrics and Gynaecology, Azienda di Rilievo Nazionale e di Alta Specializzazione (ARNAS) Garibaldi Nesima, 95124 Catania, Italy.ORCID 0000-0001-7910-0386
Giosuè Giordano IncognitoDepartment of General Surgery and Medical Surgical Specialties, University of Catania, 95123 Catania, Italy.ORCID 0000-0002-1818-0105
Attilio TuscanoDepartment of General Surgery and Medical Surgical Specialties, University of Catania, 95123 Catania, Italy.
Stefano CianciDepartment of Human Pathology of Adult and Childhood "G. Barresi", University of Messina, 98121 Messina, Italy.
Aniello Di MeglioDiagnostica Ecografica e Prenatale di A. Di Meglio, 80133 Naples, Italy.
University of Naples Federico II · ITUniversity of Catania · ITUniversity of Milan · ITAzienda di Rilievo Nazionale ed Alta Specializzazione · ITUniversity of Messina · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionA congenital intrathoracic kidney (ITK) is a rare anomaly that is recognized to have four causes: renal ectopia with an intact diaphragm, diaphragmatic eventration, diaphragmatic hernia, and traumatic diaphragmatic rupture. We report a case of a prenatal-diagnosed ITK related to a congenital diaphragmatic hernia (CDH) and conducted a systematic review of all cases of the prenatal diagnosis of this association. CASE PRESENTATION: A fetal ultrasound scan at 22 gestational weeks showed left CDH and ITK, hyperechoic left lung parenchyma, and mediastinal shift. The fetal echocardiography and karyotype were normal. Magnetic resonance imaging at 30 gestational weeks confirmed the ultrasound suspicion of left CDH in association with bowel and left kidney herniation. The fetal growth, amniotic fluid, and Doppler indices remained within the normal range over time. The woman delivered the newborn via an at-term spontaneous vaginal delivery. The newborn was stabilized and underwent non-urgent surgical correction; the postoperative course was uneventful.

conclusionsCDH is the rarest cause of ITK; we found only eleven cases describing this association. The mean gestational age at diagnosis was 29 ± 4 weeks and 4 days. There were seven cases of right and four cases of left CDH. There were associated anomalies in only three fetuses. All women delivered live babies, the herniated kidneys showed no functional damage after their surgical correction, and the prognosis was favorable after surgical repair. The prenatal diagnosis and counseling of this condition are important in planning adequate prenatal and postnatal management in order to improve neonatal outcomes.

Indexed as

case reportcongenital diaphragmatic herniacongenital malformationectopic kidneyprenatal diagnosis

Identifiers

PMID37297803
PMCPMC10253368
OpenAlexW4378078081

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.