ReviewHealthcare (Basel, Switzerland)2023
What Is Hidden behind Amputation? Quanti-Qualitative Systematic Review on Psychological Adjustment and Quality of Life in Lower Limb Amputees for Non-Traumatic Reasons.
Review in Healthcare (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
29 citing papers in PubMed, 2 syntheses or guidelines pooled it, 38 citations in OpenAlex.
- Pooled it
- Botox in below knee amputation for the management of post-operative contracture: a systematic review.The Pan African medical journal · 2024Pooled it
- Graded Motor Imagery (GRAMI Protocol) for Phantom Limb Pain: A Randomised Clinical Trial of Home-Based Intervention.European journal of pain (London, England) · 2026Trial
- Effective Interventions in Restoring Mobility and Relieving Pain After Lower Limb Amputation.Journal of orthopaedics and sports medicine · 2026Article
- Measuring satisfaction with orthotic and prosthetic devices.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2026Article
- Health-Related Quality of Life and Psychological Impact on Patients Post-Amputation Due to Diabetic Foot Ulcer.Cureus · 2026Article
- Physical and mental health outcomes in Syrian lower limb amputees: the impact of prosthetic rehabilitation in post-conflict settings.BMC musculoskeletal disorders · 2026Observational
- Clinical and psychological adjustment to prosthesis use in lower-limb amputees: focus on differences between traditional and high-technology rehabilitation.Frontiers in rehabilitation sciences · 2026Article
- Moderate and severe falls: predictive model based on six years of reports in southern Brazil.Revista da Escola de Enfermagem da U S P · 2026Article
- Baseline PTSD and depressive symptoms predict multidimensional recovery after combat-related transtibial amputation: a prospective cohort study.Frontiers in rehabilitation sciences · 2026Article
- Preoperative neutrophil-to-lymphocyte ratio is associated with amputation level progression in patients with diabetic foot.Frontiers in surgery · 2026Article
- Undernutrition is alarmingly prevalent in the dysvascular major lower limb amputation population: A prospective cohort study.PloS one · 2026Observational
- Smoking Cessation Adjuncts Are Cost Effective Prior to Elective Revascularization.Annals of vascular surgery · 2026Article
- Phantom limb telescoping in individuals with limb loss: links to anxiety, depression, and pain-related measures.Frontiers in pain research (Lausanne, Switzerland) · 2026Article
- Health-related quality of life in amputees with a microprocessor-controlled prosthetic knee measured by the EQ-5D-5L.Canadian prosthetics & orthotics journal · 2026Article
- Scapulothoracic Dissociation With Polytrauma Following a High-Velocity Motor Vehicle Collision.Cureus · 2025Article
- Regional Assessment of Lower limb Amputations in sub-Saharan Africa (RAMPs): a prospective cohort study protocol.BMJ open · 2025Article
- Psychological and Behavioral Adjustment in Patients with Non-Traumatic Lower Limb Amputation and Prosthesis: A Mixed-Method Triangulation Study.Journal of clinical medicine · 2025Article
- High-level activity and access to sport following lower limb amputation due to malignant musculoskeletal tumors versus trauma: a prospective comparative study.Archives of orthopaedic and trauma surgery · 2025Article
- Lower-Limb Amputees and Family Caregivers: Challenges, Needs, and Strategies for Empowerment-A Qualitative Study.Nursing reports (Pavia, Italy) · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveThis systematic review aims to investigate Quality of Life (QoL)/Health Related Quality of Life (HRQoL) and psychological adjustment in non-traumatic lower limb amputees (LLA).
methodsPubMed, Scopus, and Web of Science databases were used for the literature search. Studies were read and analysed using the (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) PRISMA statement procedure.
resultsThe literature search retrieved 1268 studies, of which 52 were included in the systematic review. Overall, psychological adjustment, especially depression with or without anxiety symptoms, influences the QoL/HRQoL in this clinical population. Other factors influencing QoL/HRQoL include subjective characteristics, physical aspects, the cause and level of the amputation, relational aspects, social support, and the doctor-patient relationship. In addition, the patient's emotional-motivational status, depression and/or anxiety symptoms, and acceptance play a key role in the subsequent rehabilitation process.
conclusionsIn LLA patients, psychological adjustment is a complex and multifaceted process, and QoL/HRQoL may be influenced by various factors. Shedding light on these issues may provide useful suggestions for promoting clinical and rehabilitative interventions that may be tailored and effective in this clinical population.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.