Evidence map›Paper›PMID 37297793›Full record

ReviewHealthcare (Basel, Switzerland)2023

The Role of Micronutrients in Human Papillomavirus Infection, Cervical Dysplasia, and Neoplasm.

Filippo Alberto Ferrari, Francesca Magni, Mariachiara Bosco, Giulia Biancotto, Pier Carlo Zorzato, Antonio Simone Laganà, Vito Chiantera, Ricciarda Raffaelli, Massimo Franchi, Stefano Uccella and 1 more

Open access · goldAbstract readReview
In one paragraph

Review in Healthcare (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
4.1field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it, 19 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Environment, lifestyle, and cancer in women.International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics · 2025
    Review
  8. Review
  9. Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Review
  15. The dietary inflammatory index (DIIBMC public health · 2024
    Article
  16. Review
  17. Review
  18. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Filippo Alberto FerrariDepartment of Obstetrics and Gynecology, AOUI Verona, University of Verona, 37126 Verona, Italy.ORCID 0000-0003-0726-1687
Francesca MagniDepartment of Obstetrics and Gynecology, AOUI Verona, University of Verona, 37126 Verona, Italy.
Mariachiara BoscoDepartment of Obstetrics and Gynecology, AOUI Verona, University of Verona, 37126 Verona, Italy.ORCID 0000-0002-2109-6182
Giulia BiancottoDepartment of Obstetrics and Gynecology, AOUI Verona, University of Verona, 37126 Verona, Italy.
Pier Carlo ZorzatoDepartment of Obstetrics and Gynecology, AOUI Verona, University of Verona, 37126 Verona, Italy.ORCID 0000-0002-0108-4942
Antonio Simone LaganàUnit of Gynecologic Oncology, ARNAS "Civico-Di Cristina-Benfratelli", Department of Health Promotion, Mother and Child Care, Internal Medicine and Medical Specialties (PROMISE), University of Palermo, 90127 Palermo, Italy.ORCID 0000-0003-1543-2802
Vito ChianteraUnit of Gynecologic Oncology, ARNAS "Civico-Di Cristina-Benfratelli", Department of Health Promotion, Mother and Child Care, Internal Medicine and Medical Specialties (PROMISE), University of Palermo, 90127 Palermo, Italy.ORCID 0000-0002-6294-3720
Ricciarda RaffaelliDepartment of Obstetrics and Gynecology, AOUI Verona, University of Verona, 37126 Verona, Italy.ORCID 0000-0001-6162-4114
Massimo FranchiDepartment of Obstetrics and Gynecology, AOUI Verona, University of Verona, 37126 Verona, Italy.ORCID 0000-0001-6156-158X
Stefano UccellaDepartment of Obstetrics and Gynecology, AOUI Verona, University of Verona, 37126 Verona, Italy.ORCID 0000-0002-4456-0822
Simone GarzonDepartment of Obstetrics and Gynecology, AOUI Verona, University of Verona, 37126 Verona, Italy.ORCID 0000-0002-5840-699X
University of Verona · ITUniversity of Palermo · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

There is evidence that diet and nutrition are modifiable risk factors for several cancers. In recent years, attention paid to micronutrients in gynecology has increased, especially regarding Human papillomavirus (HPV) infection. We performed a review of the literature up until December 2022, aiming to clarify the effects of micronutrients, minerals, and vitamins on the history of HPV infection and the development of cervical cancer. We included studies having as their primary objective the evaluation of dietary supplements, in particular calcium; zinc; iron; selenium; carotenoids; and vitamins A, B12, C, D, E, and K. Different oligo-elements and micronutrients demonstrated a potential protective role against cervical cancer by intervening in different stages of the natural history of HPV infection, development of cervical dysplasia, and invasive disease. Healthcare providers should be aware of and incorporate the literature evidence in counseling, although the low quality of evidence provided by available studies recommends further well-designed investigations to give clear indications for clinical practice.

Indexed as

cancer preventioncervical cancercervical dysplasiahuman papillomavirusmicronutrients

Identifiers

PMID37297793
PMCPMC10252691
OpenAlexW4379468457

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.