Evidence map›Paper›PMID 37297629›Full record

ReviewInternational journal of environmental research and public health2023

Antibiotics in Dentistry: A Narrative Review of the Evidence beyond the Myth.

Maria Contaldo, Francesco D'Ambrosio, Giuseppe A Ferraro, Dario Di Stasio, Maria Pia Di Palo, Rosario Serpico, Michele Simeone

Open access · goldAbstract readReview
In one paragraph

Review in International journal of environmental research and public health, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
46citing papers in PubMed, 1 pooled it
12.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

46 citing papers in PubMed, 1 synthesis or guideline pooled it, 68 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Review
  6. Review
  7. Article
  8. In Vitro Evaluation of the Antimicrobial Activity ofCurrent issues in molecular biology · 2026
    Article
  9. Review
  10. Evidence-Based Practice in Dentistry and OMFS: KAP Study.Journal of pharmacy & bioallied sciences · 2026
    Article
  11. Article
  12. Review
  13. Article
  14. Article
  15. Antibiotic Resistance in Dentistry: A Review.Antibiotics (Basel, Switzerland) · 2025
    Review
  16. Article
  17. Article
  18. Article
  19. Costs-Outcome Description Arising From Side Effects due the Over-Prescription of Antibiotics in Oral Healthcare in Chile.Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology · 2025
    Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Maria ContaldoMultidisciplinary Department of Medical-Surgical and Odontostomatological Specialities, University of Campania "Luigi Vanvitelli", 80138 Naples, Italy.ORCID 0000-0002-4773-6694
Francesco D'AmbrosioDepartment of Medicine, Surgery and Dentistry, University of Salerno, 84081 Salerno, Italy.ORCID 0000-0001-6161-9067
Giuseppe A FerraroMultidisciplinary Department of Medical-Surgical and Odontostomatological Specialities, University of Campania "Luigi Vanvitelli", 80138 Naples, Italy.
Dario Di StasioMultidisciplinary Department of Medical-Surgical and Odontostomatological Specialities, University of Campania "Luigi Vanvitelli", 80138 Naples, Italy.ORCID 0000-0003-3401-776X
Maria Pia Di PaloDepartment of Medicine, Surgery and Dentistry, University of Salerno, 84081 Salerno, Italy.ORCID 0000-0002-5443-8185
Rosario SerpicoMultidisciplinary Department of Medical-Surgical and Odontostomatological Specialities, University of Campania "Luigi Vanvitelli", 80138 Naples, Italy.ORCID 0000-0003-2143-3799
Michele SimeoneDepartment of Neuroscience, Reproductive Science and Dentistry, University of Naples Federico II, 80138 Naples, Italy.
University of Campania "Luigi Vanvitelli" · ITUniversity of Salerno · ITUniversity of Naples Federico II · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Antibiotics have undoubtedly revolutionized medicine and the health and survival of patients with life-threatening infections, being nonetheless free from potential adverse effects, and the risk of intestinal dysbiosis, antimicrobial resistance, and the resulting consequences for the patient's health and the public purse. The present study narratively reviewed the epidemiological data on worldwide antibiotic consumption and administration in dental practice, patients' adherence to prescriptions, the antimicrobial resistance phenomenon in dentistry, and the evidence supporting and recommending appropriate antibiotic use in dental care. Eligible systematic reviews and original studies in humans published in the English language from January 2000 to 26 January 2023 were considered. A total of 78 studies, 47 on the epidemiology of antibiotic use and prescription in dentistry, 6 on antibiotic therapy in dentistry, 12 on antibiotic prophylaxis in dentistry, 0 on adherence of dental patients to antibiotic prescription, and 13 on antimicrobial resistance in dentistry, were presently considered. Retrieved evidence revealed that antibiotics are frequently overused and misused in dental practice, dental patients frequently do not adhere to prescriptions, and antimicrobial resistance in dentistry is a still rising phenomenon also secondary to improper oral antiseptics use. The present findings highlighted the need to establish more evidence-based and accurate antibiotic prescriptions to sensitize dentists and dental patients to minimize and rationalize the use of antibiotics only when it is indicated and necessary, improve patients' adherence, and enhance knowledge and awareness of the antimicrobial resistance in dentistry.

Indexed as

Anti-Bacterial AgentsDentistsAntibiotic ProphylaxisDentistryHumansPrescriptionsAnti-Bacterial Agentsantibioticantibioticsantimicrobial stewardshipdental health servicesdentistrydentistsdrug resistance

Identifiers

PMID37297629
PMCPMC10252486
OpenAlexW4379055001

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.