Evidence map›Paper›PMID 37296958›Full record

ReviewCancers2023

Magnetic Resonance Imaging in the Clinical Care for Uveal Melanoma Patients-A Systematic Review from an Ophthalmic Perspective.

Myriam G Jaarsma-Coes, Lisa Klaassen, Marina Marinkovic, Gregorius P M Luyten, T H Khanh Vu, Teresa A Ferreira, Jan-Willem M Beenakker

Open access · goldAbstract readReview
In one paragraph

Review in Cancers, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
4.5field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Evaluation of MRI Safety of Ru-106 Eye Applicators.Ocular oncology and pathology · 2025
    Article
  10. Article
  11. Article
  12. Quantitative Perfusion-Weighted Magnetic Resonance Imaging in Uveal Melanoma.Investigative ophthalmology & visual science · 2024
    Article
  13. Review
  14. Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Myriam G Jaarsma-CoesDepartment of Ophthalmology, Leiden University Medical Center, 2333 ZA Leiden, The Netherlands.ORCID 0000-0003-3423-9370
Lisa KlaassenDepartment of Ophthalmology, Leiden University Medical Center, 2333 ZA Leiden, The Netherlands.ORCID 0000-0001-9874-7206
Marina MarinkovicDepartment of Ophthalmology, Leiden University Medical Center, 2333 ZA Leiden, The Netherlands.
Gregorius P M LuytenDepartment of Ophthalmology, Leiden University Medical Center, 2333 ZA Leiden, The Netherlands.
T H Khanh VuDepartment of Ophthalmology, Leiden University Medical Center, 2333 ZA Leiden, The Netherlands.ORCID 0000-0003-1809-4001
Teresa A FerreiraDepartment of Radiology, Leiden University Medical Center, 2333 ZA Leiden, The Netherlands.
Jan-Willem M BeenakkerDepartment of Ophthalmology, Leiden University Medical Center, 2333 ZA Leiden, The Netherlands.ORCID 0000-0003-0479-5587
Leiden University Medical Center · NL

Funding

Dutch Research Council (NWO) - Protons4Vision 14654
6 · The paper itself

Abstract

Conversely to most tumour types, magnetic resonance imaging (MRI) was rarely used for eye tumours. As recent technical advances have increased ocular MRI's diagnostic value, various clinical applications have been proposed. This systematic review provides an overview of the current status of MRI in the clinical care of uveal melanoma (UM) patients, the most common eye tumour in adults. In total, 158 articles were included. Two- and three-dimensional anatomical scans and functional scans, which assess the tumour micro-biology, can be obtained in routine clinical setting. The radiological characteristics of the most common intra-ocular masses have been described extensively, enabling MRI to contribute to diagnoses. Additionally, MRI's ability to non-invasively probe the tissue's biological properties enables early detection of therapy response and potentially differentiates between high- and low-risk UM. MRI-based tumour dimensions are generally in agreement with conventional ultrasound (median absolute difference 0.5 mm), but MRI is considered more accurate in a subgroup of anteriorly located tumours. Although multiple studies propose that MRI's 3D tumour visualisation can improve therapy planning, an evaluation of its clinical benefit is lacking. In conclusion, MRI is a complementary imaging modality for UM of which the clinical benefit has been shown by multiple studies.

Indexed as

diagnosismagnetic resonance imagingocular oncologytreatment planninguveal melanoma

Identifiers

PMID37296958
PMCPMC10252038
OpenAlexW4378905665

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.