Evidence map›Paper›PMID 37296937›Full record

ArticleCancers2023

Predictive Role of Serum Thyroglobulin after Surgery and before Radioactive Iodine Therapy in Patients with Thyroid Carcinoma.

Alberto Signore, Chiara Lauri, Arianna Di Paolo, Valeria Stati, Giuliano Santolamazza, Gabriela Capriotti, Daniela Prosperi, Anna Tofani, Stefano Valabrega, Giuseppe Campagna

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cancers, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
3.4field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it, 17 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Alberto SignoreNuclear Medicine Unit, Department of Medical-Surgical Sciences and of Translational Medicine, "Sapienza" University of Rome, 00185 Rome, Italy.ORCID 0000-0001-8923-648X
Chiara LauriNuclear Medicine Unit, Department of Medical-Surgical Sciences and of Translational Medicine, "Sapienza" University of Rome, 00185 Rome, Italy.ORCID 0000-0002-0314-5059
Arianna Di PaoloNuclear Medicine Unit, Department of Medical-Surgical Sciences and of Translational Medicine, "Sapienza" University of Rome, 00185 Rome, Italy.
Valeria StatiNuclear Medicine Unit, Department of Medical-Surgical Sciences and of Translational Medicine, "Sapienza" University of Rome, 00185 Rome, Italy.ORCID 0000-0002-4914-3948
Giuliano SantolamazzaSurgical Unit, Department of Medical-Surgical Sciences and of Translational Medicine, "Sapienza" University of Rome, 00185 Rome, Italy.
Gabriela CapriottiNuclear Medicine Unit, Department of Medical-Surgical Sciences and of Translational Medicine, "Sapienza" University of Rome, 00185 Rome, Italy.
Daniela ProsperiNuclear Medicine Unit, Sant'Andrea University Hospital, Via di Grottarossa 1035, 00189 Rome, Italy.
Anna TofaniNuclear Medicine Unit, Sant'Andrea University Hospital, Via di Grottarossa 1035, 00189 Rome, Italy.
Stefano ValabregaSurgical Unit, Department of Medical-Surgical Sciences and of Translational Medicine, "Sapienza" University of Rome, 00185 Rome, Italy.ORCID 0000-0001-5649-6891
Giuseppe CampagnaNuclear Medicine Unit, Department of Medical-Surgical Sciences and of Translational Medicine, "Sapienza" University of Rome, 00185 Rome, Italy.
Sapienza University of Rome · ITIstituti di Ricovero e Cura a Carattere Scientifico · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThyroidectomy followed by radioactive iodine therapy (RAI) is the treatment of choice for differentiated thyroid carcinoma (DTC). Serum thyroglobulin (Tg) measurement has proved to be useful for predicting persistent and/or recurrent disease during follow-up of DTC patients. In our study, we evaluated the risk of disease recurrence in patients with papillary thyroid carcinoma (PTC), who were treated with thyroidectomy and RAI, by measuring serum Tg at different time-points: at least 40 days after surgery, in euthyroidism with TSH < 1.5 and usually 30 days before RAI (Tg

methodsOne hundred and twenty-nine patients with PTC were enrolled in this retrospective study. All patients were treated with

resultsA total of 15 out of 129 patients (11.63%) developed nodal disease and 5 (3.88%) distant metastases, during the follow-up. We found that Tg

conclusionSerum Tg

Indexed as

differentiated thyroid cancerradioactive iodinethyroglobulin

Identifiers

PMID37296937
PMCPMC10251887
OpenAlexW4378882613

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.