Evidence map›Paper›PMID 37296884›Full record

ArticleCancers2023

Pathways Related to Colon Inflammation Are Associated with Colorectal Carcinoma: A Transcriptome- and Methylome-Wide Study.

Muhammad G Kibriya, Farzana Jasmine, Joel Pekow, Aaron Munoz, Christopher Weber, Maruf Raza, Mohammed Kamal, Habibul Ahsan, Marc Bissonnette

Open access · goldAbstract read
In one paragraph

Article in Cancers, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Investigating stage-specific metabolic alterations in colorectal cancer through urine metabolomics.Metabolomics : Official journal of the Metabolomic Society · 2025
    Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Muhammad G KibriyaInstitute for Population and Precision Health (IPPH), Biological Sciences Division, University of Chicago, Chicago, IL 60637, USA.ORCID 0000-0001-9784-6958
Farzana JasmineInstitute for Population and Precision Health (IPPH), Biological Sciences Division, University of Chicago, Chicago, IL 60637, USA.ORCID 0000-0002-5980-1174
Joel PekowDepartment of Medicine, Section of Gastroenterology, Hepatology and Nutrition, University of Chicago, Chicago, IL 60637, USA.
Aaron MunozInstitute for Population and Precision Health (IPPH), Biological Sciences Division, University of Chicago, Chicago, IL 60637, USA.
Christopher WeberDepartment of Pathology, University of Chicago, Chicago, IL 60637, USA.ORCID 0000-0002-2117-3184
Maruf RazaDepartment of Pathology, Jahurul Islam Medical College, Kishoregonj 2336, Bangladesh.ORCID 0000-0003-0251-4518
Mohammed KamalDepartment of Pathology, The Laboratory Dhaka, Dhaka 1205, Bangladesh.
Habibul AhsanInstitute for Population and Precision Health (IPPH), Biological Sciences Division, University of Chicago, Chicago, IL 60637, USA.
Marc BissonnetteDepartment of Medicine, Section of Gastroenterology, Hepatology and Nutrition, University of Chicago, Chicago, IL 60637, USA.
Chicago Department of Public Health · USUniversity of Chicago · USUniversity of Dhaka · BD

Funding

ULTRASTRUCTURE AND CYTOMORPHOLOGY COREP30DK042086 · NIDDK · UNIVERSITY OF CHICAGO · PI LIU, CAMBRIAN YANGSHAO · 1990 to 2025
$29.8M
Pilot Program CoreP30ES027792 · NIEHS · UNIVERSITY OF CHICAGO · PI Gokhan M. Mutlu, Gail S Prins · 2017 to 2026
$13.6M
Bangladesh Center of Research Excellence in Non-communicable Disease- Planning UnitP20CA210305 · NCI · UNIVERSITY OF CHICAGO · PI AHSAN, HABIBUL · 2016 to 2017
$524k
NIDDK NIH HHS P30 DK042086NIH HHS P20CA210305NIH HHS P30ES027792
6 · The paper itself

Abstract

The association of chronic inflammation with colorectal carcinoma (CRC) development is well known in ulcerative colitis (UC). However, the role of inflammatory changes in sporadic CRC pathogenesis is less widely appreciated. In this study, in the first step using RNA-seq, we identified gene-pathway-level changes in UC-associated CRC (UC CRC,

Indexed as

colorectal carcinomaIL-17inflammationmethylomenitrogen metabolismproteasomeRNA-seqsulfur metabolismtranscriptomiculcerative colitis

Identifiers

PMID37296884
PMCPMC10251872
OpenAlexW4378377958

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.