Evidence map›Paper›PMID 37296772›Full record

ArticleDiagnostics (Basel, Switzerland)2023

Blood Basophils Relevance in Chronic Rhinosinusitis with Aspirin-Exacerbated Respiratory Disease.

Giuseppe Brescia, Cristoforo Fabbris, Leonardo Calvanese, Luigia Bandolin, Barbara Pedruzzi, Valerio Maria Di Pasquale Fiasca, Silvia Marciani, Francesca Mularoni, Fabio Degli Esposti Pallotti, Michael Negrisolo and 3 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Diagnostics (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.5field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 2 institutions in 1 country.

Giuseppe BresciaENT Unit, Department of Surgery, Ospedali Riuniti Padova Sud, 35043 Padova, Italy.
Cristoforo FabbrisENT Unit, Department of Surgery, Ospedali Riuniti Padova Sud, 35043 Padova, Italy.ORCID 0000-0002-4476-9802
Leonardo CalvaneseENT Unit, Department of Surgery, Ospedali Riuniti Padova Sud, 35043 Padova, Italy.
Luigia BandolinENT Unit, Department of Surgery, Ospedali Riuniti Padova Sud, 35043 Padova, Italy.
Barbara PedruzziENT Unit, Department of Surgery, Ospedali Riuniti Padova Sud, 35043 Padova, Italy.
Valerio Maria Di Pasquale FiascaDepartment of Neuroscience DNS, Section of Otolaryngology, Padova University, 35100 Padova, Italy.
Silvia MarcianiDepartment of Neuroscience DNS, Section of Otolaryngology, Padova University, 35100 Padova, Italy.ORCID 0000-0002-7623-6963
Francesca MularoniDepartment of Neuroscience DNS, Section of Otolaryngology, Padova University, 35100 Padova, Italy.
Fabio Degli Esposti PallottiDepartment of Neuroscience DNS, Section of Otolaryngology, Padova University, 35100 Padova, Italy.
Michael NegrisoloDepartment of Neuroscience DNS, Padova University, 35100 Padova, Italy.
Giacomo SpinatoDepartment of Neuroscience DNS, Section of Otolaryngology, Padova University, 35100 Padova, Italy.
Anna Chiara FrigoDepartment of Cardiac-Thoracic-Vascular Sciences and Public Health, Padova University, 35100 Padova, Italy.ORCID 0000-0001-9705-4459
Gino MarioniPhoniatrics and Audiology Unit, Department of Neuroscience DNS, Padova University, 31100 Treviso, Italy.ORCID 0000-0001-8751-0588
University of Padua · ITAzienda Ospedale - Università Padova · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aspirin-exacerbated respiratory disease (AERD) is characterized by eosinophilic asthma, chronic rhinosinusitis with nasal polyps (CRSwNP) and intolerance to cyclooxygenase-1 inhibitors. Interest is emerging in studying the role of circulating inflammatory cells in CRSwNP pathogenesis and its course, as well as their potential use for a patient-tailored approach. By releasing IL-4, basophils play a crucial role in activating the Th2-mediated response. The main aim of this study was to, first, investigate the level of the pre-operative blood basophils' values, blood basophil/lymphocyte ratio (bBLR) and blood eosinophil-to-basophil ratio (bEBR) as predictors of recurrent polyps after endoscopic sinus surgery (ESS) in AERD patients. The secondary aim was to compare the blood basophil-related variables of the AERD series (study group) with those of a control group of 95 consecutive cases of histologically non-eosinophilic CRSwNP. The AERD group showed a higher recurrence rate than the control group (

Indexed as

AERDbasophilsblood cell countCRSwNPeosinophilsnasal polyposis

Identifiers

PMID37296772
PMCPMC10252406
OpenAlexW4378906200

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.