ArticleDiagnostics (Basel, Switzerland)2023
Association of the Bacteria of the Vermiform Appendix and the Peritoneal Cavity with Complicated Acute Appendicitis in Children.
Article in Diagnostics (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed, 11 citations in OpenAlex.
- Microbial profiles in pediatric complicated appendicitis: a systematic review and meta-analysis.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2026Review
- Laparoscopic Methylene Blue Photodynamic Therapy for Intraabdominal Infection: A Preclinical Feasibility Study in a Rabbit Model of Perforated Appendicitis.Lasers in surgery and medicine · 2026Article
- Linking Antimicrobial Agent Resistance Profiles to Clinical Outcomes in Pediatric Perforated Appendicitis.Surgical infections · 2026Article
- Bacterial Etiology and Antimicrobial Susceptibility Patterns in Pediatric Intra-Abdominal Infections-Implications for Empirical Treatment and Antimicrobial Stewardship.Pharmaceuticals (Basel, Switzerland) · 2026Article
- Nutritional Status as a Risk Factor for Appendiceal Perforation in Pediatric Acute Appendicitis: Systematic Review.Children (Basel, Switzerland) · 2026Review
- Bacterial pathogens and antimicrobial susceptibility profiles in acute appendicitis in children: a retrospective study at a tertiary hospital in Ningbo, China.Frontiers in pediatrics · 2026Article
- Pneumatosis Intestinalis Secondary to Appendicitis: What Do We Know?Digestive diseases and sciences · 2025Review
- Type and antibiotic susceptibility of bacteria cultured in paediatric acute appendicitis.Southern African journal of infectious diseases · 2025Article
- Case Series of Acute Appendicitis Associated With Waterborne Pathogen Exposure in College Students.Cureus · 2025Article
- MaskAppendix: Backbone-Enriched Mask R-CNN Based on Grad-CAM for Automatic Appendix Segmentation.Diagnostics (Basel, Switzerland) · 2024Article
- A Novel Deep Learning Approach for the Automatic Diagnosis of Acute Appendicitis.Journal of clinical medicine · 2024Article
- Perforated Appendicitis in Children: Management, Microbiology, and Antibiotic Stewardship.Paediatric drugs · 2024Review
- Exceptional association of two species of bacteria causing acute appendicitis: Haemophilus influenzae and Enterobacter cloacae.Access microbiology · 2024Article
- The Impact of Laparoscopic Appendectomy and Open Appendectomy on B7-H3-Mediated Intrinsic Immune Response in Children with Acute Suppurative Appendicitis.Journal of inflammation research · 2024Article
- Outcome of intra-operative Purulent Peritoneal Fluid Aspirate Culture Results during Appendicectomy in Patients' Management.Nigerian medical journal : journal of the Nigeria Medical AssociationArticle
Corrections and comments
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Authors and funding
12 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPrimary infection has been questioned as the pathogenetic cause of acute appendicitis. We attempted to identify the bacteria involved and to investigate if their species, types, or combinations affected the severity of acute appendicitis in children.
methodsSamples from both the appendiceal lumen and the peritoneal cavity of 72 children who underwent appendectomy were collected to perform bacterial culture analysis. The outcomes were studied to identify if and how they were associated with the severity of the disease. Regression analysis was performed to identify any risk factors associated with complicated appendicitis.
results
conclusionsPolymicrobial presentation and Gram-negative bacteria are associated with complicated appendicitis. Antibiotic regimens should target the combinations of the most frequently identified pathogens, speculating the value of early antipseudomonal intervention.
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Registered trials
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