Evidence map›Paper›PMID 37296461›Full record

ArticleGenome biology2023

Matchtigs: minimum plain text representation of k-mer sets.

Sebastian Schmidt, Shahbaz Khan, Jarno N Alanko, Giulio E Pibiri, Alexandru I Tomescu

Abstract read
In one paragraph

Article in Genome biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Elucidating Transitions ofJournal of computational biology : a journal of computational molecular cell biology · 2026
    Article
  3. Article
  4. Prokrustean Graph: A substring index for rapid k-mer size analysis.bioRxiv : the preprint server for biology · 2025
    Article
  5. A survey of k-mer methods and applications in bioinformatics.Computational and structural biotechnology journal · 2024
    Review
  6. Article
  7. Article
  8. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors.

Sebastian SchmidtDepartment of Computer Science, University of Helsinki, Helsinki, Finland. sebastian.schmidt@helsinki.fi.ORCID 0000-0003-4878-2809
Shahbaz KhanDepartment of Computer Science and Engineering, Indian Institute of Technology Roorkee, Roorkee, India. shahbaz.khan@cs.iitr.ac.in.ORCID 0000-0001-9352-0088
Jarno N AlankoDepartment of Computer Science, University of Helsinki, Helsinki, Finland.ORCID 0000-0002-8003-9225
Giulio E PibiriDepartment of Environmental Sciences, Informatics and Statistics, Ca' Foscari University of Venice, Venice, Italy.ORCID 0000-0003-0724-7092
Alexandru I TomescuDepartment of Computer Science, University of Helsinki, Helsinki, Finland. alexandru.tomescu@helsinki.fi.ORCID 0000-0002-5747-8350

Funding

Academy of Finland 322595Academy of Finland 328877European Research Council 851093H2020 European Research Council 851093Horizon 2020 Framework Programme 101006879
6 · The paper itself

Abstract

We propose a polynomial algorithm computing a minimum plain-text representation of k-mer sets, as well as an efficient near-minimum greedy heuristic. When compressing read sets of large model organisms or bacterial pangenomes, with only a minor runtime increase, we shrink the representation by up to 59% over unitigs and 26% over previous work. Additionally, the number of strings is decreased by up to 97% over unitigs and 90% over previous work. Finally, a small representation has advantages in downstream applications, as it speeds up SSHash-Lite queries by up to 4.26× over unitigs and 2.10× over previous work.

Indexed as

AlgorithmsSoftwareBacteriaSequence Analysis, DNAChinese postman problemGenomic sequencesGraph algorithmk-mer setsMinimum-cost flowPlain text compressionSequence analysis

Identifiers

PMID37296461
PMCPMC10251615

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.