Evidence map›Paper›PMID 37296197›Full record

ArticleScientific reports2023

Prevalence and therapeutic impact of adverse life event reexperiencing under ceremonial ayahuasca.

Brandon Weiss, Aleksandra Wingert, David Erritzoe, W Keith Campbell

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
9.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 30 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. Traumatic Psychedelic Experiences.Current topics in behavioral neurosciences · 2026
    Review
  6. Article
  7. Article
  8. Article
  9. Decreased COCommunications psychology · 2025
    Article
  10. Article
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Brandon WeissDivision of Psychiatry, Imperial College London, London, UK. bw64357@gmail.com.
Aleksandra WingertDivision of Psychiatry, Imperial College London, London, UK.
David ErritzoeDivision of Psychiatry, Imperial College London, London, UK.ORCID 0000-0002-7022-6211
W Keith CampbellUniversity of Georgia, Athens, GA, USA.
Imperial College London · GBUniversity of Georgia · US

Funding

Examining Neural Modulatory Effects of Serotonergic Psychedelic Compounds in Relation to NeuroticismF32DA055459 · NIDA · IMPERIAL COLLEGE OF SCIENCE, TECHNOLOGY AND MEDICINE · PI WEISS, BRANDON · 2022 to 2022
$53k
NIDA NIH HHS F32 DA055459
6 · The paper itself

Abstract

The present study examined the safety and efficacy of the ceremonial use of ayahuasca in relation to reports of heightened life event reexperiencing under psychedelics. The study examined (1) the prevalence of specific types of adverse life event reexperiencing, (2) characteristics predictive of reexperiencing, (3) the psychological character of reexperiencing, and (4) the impact of reexperiencing on mental health. Participants were recruited from three ayahuasca healing and spiritual centers in South and Central America (N = 33 military veterans, 306 non-veterans) using self-report data at three timepoints (Pre-retreat, Post-retreat, 3-months post-retreat). Reexperiencing adverse life events under ayahuasca was common, with women showing particularly high probability of reexperiencing sexual assault, veterans reexperiencing combat-related trauma, and individuals with a self-reported lifetime diagnosis of post-traumatic stress disorder exhibiting a substantively higher prevalence of reexperiencing. Reexperiencing was associated with states of cognitive reappraisal, psychological flexibility, and discomfort during ceremonies, and participants who reexperienced adverse life events exhibited greater reductions in trait neuroticism following their ceremonies. Clinical implications of these results for the application of psychedelics to mood and stress disorders are discussed.

Indexed as

BanisteriopsisHallucinogensStress Disorders, Post-TraumaticVeteransFemaleHumansPrevalenceHallucinogens

Identifiers

PMID37296197
PMCPMC10256717
OpenAlexW4380089845

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.