ArticleNature communications2023
Intracranial electrophysiological and structural basis of BOLD functional connectivity in human brain white matter.
Article in Nature communications, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.
What it found
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Who cites it
34 citing papers in PubMed, 52 citations in OpenAlex.
- Functional near-infrared spectroscopy: Systematic mapping of abnormal brain function features in neurological disorders.Neural regeneration research · 2026Article
- A Distinct Second Spectral Peak in White Matter BOLD Signals: Mathematical Modeling, Spatial Distribution and Age-Related Evolution.Research square · 2026Article
- Electrophysiological features of signals recorded from white matter.bioRxiv : the preprint server for biology · 2026Article
- Cell-type and spatiotemporal transcriptional signatures of white matter morphometric similarity network alterations in major depressive disorder.Psychological medicine · 2026Article
- Developmental changes of the white matter functional connectome.Molecular psychiatry · 2026Article
- The nature and interpretation of BOLD signals in white matter - A review.Magnetic resonance imaging · 2026Review
- Body weight-related alterations in white matter functional connectivity in children: An fMRI study.BMC neurology · 2026Article
- An applied study of blood oxygenation level-dependent and arterial spin labeling in early transplant renal function based on renal magnetic resonance angiography examination.Quantitative imaging in medicine and surgery · 2026Article
- Beyond scaling: how brains reorganize to support higher intelligence.Frontiers in systems neuroscience · 2026Article
- Article
- Early brain changes in Lyme disease are associated with clinical outcomes.Brain, behavior, & immunity - health · 2025Article
- Investigation of the large-scale white-matter functional networks in spinocerebellar ataxia type 3.Quantitative imaging in medicine and surgery · 2025Article
- Observational
- Functional MRI signals as fast as 1Hz are coupled to brain states and predict spontaneous neural activity.bioRxiv : the preprint server for biology · 2025Article
- Integrating direct electrical stimulation with brain connectivity predicts lesion-induced language impairment and recovery.Communications medicine · 2025Article
- Localization of the Epileptogenic Zone Using Neural Spatial Volatility in Epilepsy Surgery.Neurology · 2025Observational
- Cortical modulation of resting state BOLD signals in white matter.Scientific reports · 2025Article
- Very High-Frequency Oscillations in Mesial Temporal Lobe Epilepsy: Identifying the Epileptogenic Zone.Annals of clinical and translational neurology · 2025Article
- White matter dysfunction in Alzheimer's disease is associated with disease-related transcriptomic signatures.Communications biology · 2025Article
- Intermittent Fasting Enhances Motor Coordination Through Myelin Preservation in Aged Mice.Aging cell · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
12 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
While functional MRI (fMRI) studies have mainly focused on gray matter, recent studies have consistently found that blood-oxygenation-level-dependent (BOLD) signals can be reliably detected in white matter, and functional connectivity (FC) has been organized into distributed networks in white matter. Nevertheless, it remains unclear whether this white matter FC reflects underlying electrophysiological synchronization. To address this question, we employ intracranial stereotactic-electroencephalography (SEEG) and resting-state fMRI data from a group of 16 patients with drug-resistant epilepsy. We find that BOLD FC is correlated with SEEG FC in white matter, and this result is consistent across a wide range of frequency bands for each participant. By including diffusion spectrum imaging data, we also find that white matter FC from both SEEG and fMRI are correlated with white matter structural connectivity, suggesting that anatomical fiber tracts underlie the functional synchronization in white matter. These results provide evidence for the electrophysiological and structural basis of white matter BOLD FC, which could be a potential biomarker for psychiatric and neurological disorders.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.