Evidence map›Paper›PMID 37296098›Full record

ArticleNature communications2023

Substrate binding-induced conformational transitions in the omega-3 fatty acid transporter MFSD2A.

Shana Bergman, Rosemary J Cater, Ambrose Plante, Filippo Mancia, George Khelashvili

Open access · goldAbstract read
In one paragraph

Article in Nature communications, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
2.9field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 19 citations in OpenAlex.

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  10. Molecular basis of Spns1-mediated lysophospholipid transport from the lysosome.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Shana Bergman *Department of Physiology and Biophysics, Weill Cornell Medical College, Cornell University, New York, NY, 10065, USA.
Rosemary J Cater *Department of Physiology and Cellular Biophysics, Columbia University, New York, NY, 10032, USA.
Ambrose PlanteDepartment of Physiology and Biophysics, Weill Cornell Medical College, Cornell University, New York, NY, 10065, USA.
Filippo ManciaDepartment of Physiology and Cellular Biophysics, Columbia University, New York, NY, 10032, USA.
George KhelashviliDepartment of Physiology and Biophysics, Weill Cornell Medical College, Cornell University, New York, NY, 10065, USA. gek2009@med.cornell.edu.ORCID 0000-0001-7235-8579
Cornell University · USColumbia University · US

Funding

Genetic and Environmental Influences on AddictionT32DA039080 · NIDA · WEILL MEDICAL COLL OF CORNELL UNIV · PI Teresa A Milner · 2017 to 2026
$1.4M
Molecular mechanism of omega-3 fatty acid transport into the brainR21MH125649 · NIMH · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI MANCIA, FILIPPO · 2021 to 2022
$446k
NIDA NIH HHS T32 DA039080NIMH NIH HHS R21 MH125649
6 · The paper itself

Abstract

Major Facilitator Superfamily Domain containing 2 A (MFSD2A) is a transporter that is highly enriched at the blood-brain and blood-retinal barriers, where it mediates Na

Indexed as

Fatty Acids, Omega-3SymportersBiological TransportBrainMembrane Transport ProteinsMolecular Dynamics SimulationFatty Acids, Omega-3Membrane Transport ProteinsSymporters

Identifiers

PMID37296098
PMCPMC10250862
OpenAlexW4380088098

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.