Evidence map›Paper›PMID 37295686›Full record

ArticleChemosphere2023

Urinary arsenic and spontaneous pregnancy loss - a hypothesis-generating case-control investigation in western Romania.

Iulia A Neamtiu, Michael S Bloom, Juliana M Clark, Cristian Pop, Olivian Marincas, Ioana Berindan-Neagoe, Cornelia Braicu, Eugen S Gurzau

Open access · greenAbstract read
In one paragraph

Article in Chemosphere, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Iulia A NeamtiuHealth Department, Environmental Health Center Part of ALS, 58 Busuiocului Street, 400240, Cluj-Napoca, Romania; Faculty of Environmental Science and Engineering, Babes-Bolyai University, 30 Fantanele Street, 400294, Cluj-Napoca, Romania. Electronic address: iulia.neamtiu@alsglobal.com.
Michael S BloomDepartment of Global and Community Health, George Mason University, 4400 University Dr, Fairfax, VA, United States. Electronic address: mbloom22@gmu.edu.
Juliana M ClarkDepartment of Global and Community Health, George Mason University, 4400 University Dr, Fairfax, VA, United States. Electronic address: jclark69@gmu.edu.
Cristian PopPhysico-chemical and Biotoxicological Analysis Laboratory, Environmental Health Center Part of ALS, 58 Busuiocului Street, 400240, Cluj-Napoca, Romania. Electronic address: cristian.pop@alsglobal.com.
Olivian MarincasPhysico-chemical and Biotoxicological Analysis Laboratory, Environmental Health Center Part of ALS, 58 Busuiocului Street, 400240, Cluj-Napoca, Romania. Electronic address: olivian.marincas@alsglobal.com.
Ioana Berindan-NeagoeResearch Center for Functional Genomics, Biomedicine and Translational Medicine, Iuliu Hatieganu University of Medicine and Pharmacy, 3-5 Clinicilor Street, 400347, Cluj-Napoca, Romania. Electronic address: ioananeagoe29@gmail.com.
Cornelia BraicuResearch Center for Functional Genomics, Biomedicine and Translational Medicine, Iuliu Hatieganu University of Medicine and Pharmacy, 3-5 Clinicilor Street, 400347, Cluj-Napoca, Romania. Electronic address: braicucornelia@yahoo.com.
Eugen S GurzauResearch Center for Functional Genomics, Biomedicine and Translational Medicine, Iuliu Hatieganu University of Medicine and Pharmacy, 3-5 Clinicilor Street, 400347, Cluj-Napoca, Romania. Electronic address: egurzau@ehc.ro.
Iuliu Hațieganu University of Medicine and Pharmacy · ROTechnical University of Cluj-Napoca · ROGeorge Mason University · US

Funding

Arsenic Contaminated Water Consumption & Spontaneous Pregnancy Loss in RomaniaR03ES020446 · NIEHS · STATE UNIVERSITY OF NEW YORK AT ALBANY · PI BLOOM, MICHAEL S · 2011 to 2012
$151k
NIEHS NIH HHS R03 ES020446
6 · The paper itself

Abstract

Arsenic occurs as a natural contaminant of drinking water supplies in arsenic endemic areas, posing a threat to public health. Our aim was to evaluate the relationship between urinary arsenic concentrations and spontaneous pregnancy loss in a population with low-moderate level drinking water arsenic exposure (mostly <10 μg/L). We enrolled 150 women with incident spontaneous pregnancy losses and 150 controls with ongoing pregnancies matched by gestational age. We measured arsenic species in urine using high performance liquid chromatography paired to inductively coupled plasma mass spectrometry. Urinary arsenic was not related to spontaneous pregnancy loss in conditional logistic regression models adjusted for confounding factors. However, a 10 μg/L increase in urinary arsenic (III + V) salt concentrations was associated with 8.00-fold (95% CI: 0.68, 3.35 × 10

Indexed as

Abortion, SpontaneousArsenicArsenicalsDrinking WaterCase-Control StudiesCotinineEnvironmental ExposureFemaleHumansPregnancyRomaniaArsenicArsenicalsCotinineDrinking WaterExposureGroundwaterInorganic arsenicPregnancy outcomesRomania

Identifiers

PMID37295686
PMCPMC10335628
OpenAlexW4379977629

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.