Evidence map›Paper›PMID 37294764›Full record

ArticleScience advances2023

Sequence variants affecting voice pitch in humans.

Rosa S Gisladottir, Agnar Helgason, Bjarni V Halldorsson, Hannes Helgason, Michal Borsky, Yu-Ren Chien, Jon Gudnason, Sigurjon A Gudjonsson, Scott Moisik, Dan Dediu and 23 more

Open access · goldAbstract read
In one paragraph

Article in Science advances, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.8field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 18 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

33 authors at 4 institutions in 3 countries.

Rosa S GisladottirdeCODE Genetics/Amgen Inc., Sturlugata 8, 101 Reykjavik, Iceland.ORCID 0000-0003-0941-1888
Agnar HelgasondeCODE Genetics/Amgen Inc., Sturlugata 8, 101 Reykjavik, Iceland.ORCID 0000-0002-8545-3767
Bjarni V HalldorssondeCODE Genetics/Amgen Inc., Sturlugata 8, 101 Reykjavik, Iceland.ORCID 0000-0003-0756-0767
Hannes HelgasondeCODE Genetics/Amgen Inc., Sturlugata 8, 101 Reykjavik, Iceland.
Michal BorskyDepartment of Engineering, Reykjavik University, Menntavegur 1, 101 Reykjavik, Iceland.
Yu-Ren ChienDepartment of Engineering, Reykjavik University, Menntavegur 1, 101 Reykjavik, Iceland.ORCID 0000-0002-2104-3814
Jon GudnasonDepartment of Engineering, Reykjavik University, Menntavegur 1, 101 Reykjavik, Iceland.ORCID 0000-0001-6560-5543
Sigurjon A GudjonssondeCODE Genetics/Amgen Inc., Sturlugata 8, 101 Reykjavik, Iceland.ORCID 0000-0001-9314-7412
Scott MoisikDivision of Linguistics and Multilingual Studies, Nanyang Technological University, 50 Nanyang Avenue, Singapore 639798, Singapore.ORCID 0000-0003-1540-1790
Dan DediuDepartment of Catalan Philology and General Linguistics, University of Barcelona, Gran Via 585, Barcelona 08007, Spain.ORCID 0000-0002-0704-6365
Gudmar ThorleifssondeCODE Genetics/Amgen Inc., Sturlugata 8, 101 Reykjavik, Iceland.ORCID 0000-0003-4623-9087
Vinicius TragantedeCODE Genetics/Amgen Inc., Sturlugata 8, 101 Reykjavik, Iceland.ORCID 0000-0002-8223-8957
Mariana BustamantedeCODE Genetics/Amgen Inc., Sturlugata 8, 101 Reykjavik, Iceland.
Gudrun A JonsdottirdeCODE Genetics/Amgen Inc., Sturlugata 8, 101 Reykjavik, Iceland.
Lilja StefansdottirdeCODE Genetics/Amgen Inc., Sturlugata 8, 101 Reykjavik, Iceland.
Gudrun RutsdottirdeCODE Genetics/Amgen Inc., Sturlugata 8, 101 Reykjavik, Iceland.ORCID 0000-0001-6723-0757
Sigurdur H MagnussondeCODE Genetics/Amgen Inc., Sturlugata 8, 101 Reykjavik, Iceland.
Marteinn HardarsondeCODE Genetics/Amgen Inc., Sturlugata 8, 101 Reykjavik, Iceland.ORCID 0000-0003-1130-8601
Egil FerkingstaddeCODE Genetics/Amgen Inc., Sturlugata 8, 101 Reykjavik, Iceland.ORCID 0000-0001-8090-7988
Gisli H HalldorssondeCODE Genetics/Amgen Inc., Sturlugata 8, 101 Reykjavik, Iceland.ORCID 0000-0001-7067-9862
Solvi RognvaldssondeCODE Genetics/Amgen Inc., Sturlugata 8, 101 Reykjavik, Iceland.ORCID 0000-0002-4376-3361
Astros SkuladottirdeCODE Genetics/Amgen Inc., Sturlugata 8, 101 Reykjavik, Iceland.ORCID 0000-0002-5048-0933
Erna V IvarsdottirdeCODE Genetics/Amgen Inc., Sturlugata 8, 101 Reykjavik, Iceland.
Gudmundur NorddahldeCODE Genetics/Amgen Inc., Sturlugata 8, 101 Reykjavik, Iceland.ORCID 0000-0002-5622-7197
Gudmundur ThorgeirssondeCODE Genetics/Amgen Inc., Sturlugata 8, 101 Reykjavik, Iceland.
Ingileif JonsdottirdeCODE Genetics/Amgen Inc., Sturlugata 8, 101 Reykjavik, Iceland.ORCID 0000-0001-8339-150X
Magnus O UlfarssondeCODE Genetics/Amgen Inc., Sturlugata 8, 101 Reykjavik, Iceland.ORCID 0000-0002-0461-040X
Hilma HolmdeCODE Genetics/Amgen Inc., Sturlugata 8, 101 Reykjavik, Iceland.ORCID 0000-0002-9517-6636
Hreinn StefanssondeCODE Genetics/Amgen Inc., Sturlugata 8, 101 Reykjavik, Iceland.ORCID 0000-0002-9331-6666
Unnur ThorsteinsdottirdeCODE Genetics/Amgen Inc., Sturlugata 8, 101 Reykjavik, Iceland.ORCID 0000-0002-7049-2827
Daniel F GudbjartssondeCODE Genetics/Amgen Inc., Sturlugata 8, 101 Reykjavik, Iceland.ORCID 0000-0002-5222-9857
Patrick SulemdeCODE Genetics/Amgen Inc., Sturlugata 8, 101 Reykjavik, Iceland.ORCID 0000-0001-7123-6123
Kari StefanssondeCODE Genetics/Amgen Inc., Sturlugata 8, 101 Reykjavik, Iceland.ORCID 0000-0003-1676-864X
deCODE Genetics (Iceland) · ISReykjavík University · ISInstitució Catalana de Recerca i Estudis Avançats · ESNanyang Technological University · SG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The genetic basis of the human vocal system is largely unknown, as are the sequence variants that give rise to individual differences in voice and speech. Here, we couple data on diversity in the sequence of the genome with voice and vowel acoustics in speech recordings from 12,901 Icelanders. We show how voice pitch and vowel acoustics vary across the life span and correlate with anthropometric, physiological, and cognitive traits. We found that voice pitch and vowel acoustics have a heritable component and discovered correlated common variants in

Indexed as

Speech AcousticsVoiceAcousticsHumansSpeech

Identifiers

PMID37294764
PMCPMC10256171
OpenAlexW4380080286

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.