Evidence map›Paper›PMID 37294753›Full record

ArticleScience advances2023

Decoding and synthesizing tonal language speech from brain activity.

Yan Liu, Zehao Zhao, Minpeng Xu, Haiqing Yu, Yanming Zhu, Jie Zhang, Linghao Bu, Xiaoluo Zhang, Junfeng Lu, Yuanning Li and 2 more

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Science advances, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07460037 (Investigation of Chinese-Specific Speech Imagery Encoding and Decoding Using High-Density Electrocorticography), which is not on this map. Cited by 22 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 1 pooled it
8.1field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07460037 narecruitingnot on this mapstarted 2026, after this paper: background citation

Investigation of Chinese-Specific Speech Imagery Encoding and Decoding Using High-Density Electrocorticography

TypeinterventionalSponsorSecond Affiliated Hospital, Zhejiang University, School of MedicineRan2026 to 2028Enrolled50ConditionsAphasia, Dysarthria, ALS, Speech and Language DisorderArmsIntraoperative high-density ECoG recording, Permanent high-density ECoG implantation
3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 1 synthesis or guideline pooled it, 41 citations in OpenAlex.

  1. Pooled it
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  16. Acoustic Inspired Brain-to-Sentence Decoder for Logosyllabic Language.Cyborg and bionic systems (Washington, D.C.) · 2025
    Article
  17. Article
  18. [Applications and prospects of electroencephalography technology in neurorehabilitation assessment and treatment].Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi · 2024
    Review
  19. Brain-computer Interaction in the Smart Era.Current medical science · 2024
    Review
  20. An instantaneous voice synthesis neuroprosthesis.bioRxiv : the preprint server for biology · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 1 country.

Yan LiuDepartment of Neurosurgery, Huashan Hospital, Shanghai Medical College, Fudan University, Shanghai 200040, China.ORCID 0000-0001-9795-3390
Zehao ZhaoDepartment of Neurosurgery, Huashan Hospital, Shanghai Medical College, Fudan University, Shanghai 200040, China.ORCID 0000-0002-7100-4530
Minpeng XuDepartment of Biomedical Engineering, College of Precision Instruments and Optoelectronics Engineering, Tianjin University, Tianjin 300041, China.ORCID 0000-0001-6746-4828
Haiqing YuDepartment of Biomedical Engineering, College of Precision Instruments and Optoelectronics Engineering, Tianjin University, Tianjin 300041, China.ORCID 0000-0001-7907-1191
Yanming ZhuDepartment of Neurosurgery, Huashan Hospital, Shanghai Medical College, Fudan University, Shanghai 200040, China.ORCID 0000-0002-6862-8123
Jie ZhangDepartment of Neurosurgery, Huashan Hospital, Shanghai Medical College, Fudan University, Shanghai 200040, China.ORCID 0000-0002-6805-8474
Linghao BuDepartment of Neurosurgery, Huashan Hospital, Shanghai Medical College, Fudan University, Shanghai 200040, China.
Xiaoluo ZhangDepartment of Neurosurgery, Huashan Hospital, Shanghai Medical College, Fudan University, Shanghai 200040, China.
Junfeng LuDepartment of Neurosurgery, Huashan Hospital, Shanghai Medical College, Fudan University, Shanghai 200040, China.ORCID 0000-0002-6091-5742
Yuanning LiSchool of Biomedical Engineering, ShanghaiTech University, Shanghai 201210, China.ORCID 0000-0003-3277-0600
Dong MingDepartment of Biomedical Engineering, College of Precision Instruments and Optoelectronics Engineering, Tianjin University, Tianjin 300041, China.
Jinsong WuDepartment of Neurosurgery, Huashan Hospital, Shanghai Medical College, Fudan University, Shanghai 200040, China.ORCID 0000-0001-7854-9798
Fudan University · CNTianjin University · CNShanghaiTech University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Recent studies have shown that the feasibility of speech brain-computer interfaces (BCIs) as a clinically valid treatment in helping nontonal language patients with communication disorders restore their speech ability. However, tonal language speech BCI is challenging because additional precise control of laryngeal movements to produce lexical tones is required. Thus, the model should emphasize the features from the tonal-related cortex. Here, we designed a modularized multistream neural network that directly synthesizes tonal language speech from intracranial recordings. The network decoded lexical tones and base syllables independently via parallel streams of neural network modules inspired by neuroscience findings. The speech was synthesized by combining tonal syllable labels with nondiscriminant speech neural activity. Compared to commonly used baseline models, our proposed models achieved higher performance with modest training data and computational costs. These findings raise a potential strategy for approaching tonal language speech restoration.

Indexed as

LanguageSpeechBrainHumansNeural Networks, Computer

Identifiers

PMID37294753
PMCPMC10256166
OpenAlexW4379983773

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.