ReviewJournal of natural medicines2023
Tigliane and daphnane diterpenoids from Thymelaeaceae family: chemistry, biological activity, and potential in drug discovery.
Review in Journal of natural medicines, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
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Who cites it
15 citing papers in PubMed, 36 citations in OpenAlex.
- Phytochemical study ofPharmaceutical biology · 2026Article
- Liquid chromatography-mass spectrometry-based automated annotation program-assisted structural characterization of daphnane diterpenoids from Daphne genkwa.Journal of natural medicines · 2026Article
- Evolution of a Synthetic Strategy for Complex Diterpenes fromJournal of the American Chemical Society · 2026Article
- Identification of Daphnane Diterpenoids from Flower Buds and Blooming Flowers ofPlants (Basel, Switzerland) · 2025Article
- Automated annotation of complex natural products using a modular fragmentation-based structure assembly (MFSA) strategy.Science advances · 2025Article
- Review
- Anti-HIV diterpenoids from Daphne pseudomezereum.Phytochemistry · 2025Article
- Anti-HIV Activity of Tigliane Derivatives fromMolecules (Basel, Switzerland) · 2025Article
- Review
- Topological Heterogeneity of Protein Kinase C Modulators in Human T-Cells Resolved with In-Cell Dynamic Nuclear Polarization NMR Spectroscopy.Journal of the American Chemical Society · 2024Article
- Daphnane diterpenoid orthoesters with an odd-numbered aliphatic side chain from Daphne pedunculata.Journal of natural medicines · 2024Article
- Unveiling the pharmacological potential of plant triterpenoids in breast cancer management: an updated review.Naunyn-Schmiedeberg's archives of pharmacology · 2024Review
- LC-MS identification, isolation, and structural elucidation of anti-HIV macrocyclic daphnane orthoesters from Edgeworthia chrysantha.Fitoterapia · 2024Article
- Isolation and Identification of 12-Deoxyphorbol Esters fromPlants (Basel, Switzerland) · 2023Article
- Identification of Daphnane Diterpenoids fromPlants (Basel, Switzerland) · 2023Article
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
Tigliane and daphnane diterpenoids are characteristically distributed in plants of the Thymelaeaceae family as well as the Euphorbiaceae family and are structurally diverse due to the presence of polyoxygenated functionalities in the polycyclic skeleton. These diterpenoids are known as toxic components, while they have been shown to exhibit a wide variety of biological activities, such as anti-cancer, anti-HIV, and analgesic activity, and are attracting attention in the field of natural product drug discovery. This review focuses on naturally occurring tigliane and daphnane diterpenoids from plants of the Thymelaeaceae family and provides an overview of their chemical structure, distribution, isolation, structure determination, chemical synthesis, and biological activities, with a prime focus on the recent findings.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.