Evidence map›Paper›PMID 37294378›Full record

ArticleAmino acids2023

Stereoselective synthesis of S-norvaline and related amino acids through a common intermediate.

José C Espinoza-Hicks, David Chavez-Flores, Gerardo Zaragoza-Galan, Alejandro A Camacho-Davila

Abstract read
PubMed Publisher
In one paragraph

Article in Amino acids, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.4field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 3 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

José C Espinoza-HicksFacultad de Ciencias Químicas, Universidad Autónoma de Chihuahua, Campus Universitario 2, 31115, Chihuahua, Chih, Mexico.
David Chavez-FloresFacultad de Ciencias Químicas, Universidad Autónoma de Chihuahua, Campus Universitario 2, 31115, Chihuahua, Chih, Mexico.
Gerardo Zaragoza-GalanFacultad de Ciencias Químicas, Universidad Autónoma de Chihuahua, Campus Universitario 2, 31115, Chihuahua, Chih, Mexico.
Alejandro A Camacho-DavilaFacultad de Ciencias Químicas, Universidad Autónoma de Chihuahua, Campus Universitario 2, 31115, Chihuahua, Chih, Mexico. acamach@uach.mx.
Autonomous University of Chihuahua · MX

Funding

Consejo Nacional de Ciencia y Tecnología CB-2015-01 255121
6 · The paper itself

Abstract

A divergent, enantioselective synthetic strategy is reported to produce the non-proteinogenic, biologically active natural amino acids norvaline, 5-hydroxy-4-oxo-L-norvaline, and ɣ-oxonorvaline. These were synthesized in good yields (45-75%) from the common starting material (S)-allylglycine obtained by asymmetric transfer allylation of glycine Schiff base using the Corey catalyst derived from cinchonidine in more than 97% enantiomeric excess.

Indexed as

Amino AcidsValineAllylglycineCatalysisGlycineStereoisomerismAllylglycineAmino AcidsGlycinenorvalineValine5-Hydroxy-4-oxo-S-norvalineAllylglycineAmino acidɣ-oxonorvalineNorvalinePhase transfer catalysis

Identifiers

PMID37294378
OpenAlexW4379966547

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.