Evidence map›Paper›PMID 37293735›Full record

ArticleCerebral cortex (New York, N.Y. : 1991)2023

Thalamo-cortical and cerebello-cortical functional connectivity in development.

Carolina Badke D'Andrea, Scott Marek, Andrew N Van, Ryland L Miller, Eric A Earl, Stephanie B Stewart, Nico U F Dosenbach, Bradley L Schlaggar, Timothy O Laumann, Damien A Fair and 2 more

Abstract read
In one paragraph

Article in Cerebral cortex (New York, N.Y. : 1991), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
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  6. Article
  7. Article
  8. Article
  9. Review
  10. The Evolving Cerebellar and Cerebello-cortical Functional Connectivity Architecture during Infancy.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025
    Article
  11. Functional Neuroanatomy of Tics: A Brain Network Perspective.The Psychiatric clinics of North America · 2025
    Review
  12. Article
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Carolina Badke D'AndreaDepartment of Cognitive Science, University of California San Diego, La Jolla, CA 92093, United States.ORCID 0000-0002-6240-8832
Scott MarekDepartment of Radiology, Washington University School of Medicine, St. Louis, MO 63110, United States.
Andrew N VanDepartment of Neurology, Washington University School of Medicine, St. Louis, MO 63110, United States.
Ryland L MillerDepartment of Psychiatry, Washington University School of Medicine, St. Louis, MO 63110, United States.
Eric A EarlData Science and Sharing Team, National Institute of Mental Health, NIH, DHHS, Bethesda, MD 20899, United States.
Stephanie B StewartDepartment of Psychiatry, University of Colorado School of Medicine, Aurora, CO 80045, United States.
Nico U F DosenbachDepartment of Radiology, Washington University School of Medicine, St. Louis, MO 63110, United States.
Bradley L SchlaggarKennedy Krieger Institute, Baltimore, MD 21205, United States.
Timothy O LaumannDepartment of Psychiatry, Washington University School of Medicine, St. Louis, MO 63110, United States.
Damien A FairInstitute of Child Development, College of Education and Human Development, University of Minnesota, Minneapolis, MN 55455, United States.
Evan M GordonDepartment of Radiology, Washington University School of Medicine, St. Louis, MO 63110, United States.ORCID 0000-0002-2276-5237
Deanna J GreeneDepartment of Cognitive Science, University of California San Diego, La Jolla, CA 92093, United States.ORCID 0000-0002-0739-7771

Funding

Sleep and Circadian Dysfunction, Brain and Neurobehavioral Development in AutismP50HD103538 · NICHD · HUGO W. MOSER RES INST KENNEDY KRIEGER · PI Stewart H Mostofsky · 2020 to 2026
$9.9M
Identification of outcome-based sub-populations using deep phenotyping and precision functional mapping across ADHD and ASDR01MH096773 · NIMH · UNIVERSITY OF MINNESOTA · PI DOSENBACH, NICO, FAIR, DAMIEN A · 2012 to 2024
$9.4M
Developmental Neuroscience and Child PsychopathologyT32MH100019 · NIMH · WASHINGTON UNIVERSITY · PI Deanna Barch, JOAN L. LUBY · 2013 to 2026
$4.8M
DEVELOPMENT OF SKILLED READING: FMRI STUDIESR01HD057076 · NICHD · WASHINGTON UNIVERSITY · PI SCHLAGGAR, BRADLEY L · 2008 to 2012
$1.7M
Neurodevelopmental profiles related to transdiagnostic and disorder-specific symptoms of anxiety and depressionR00MH121518 · NIMH · WASHINGTON UNIVERSITY · PI MAREK, SCOTT · 2022 to 2024
$744k
PREDICTING OUTCOME IN CHILDREN WITH TIC DISORDERS USING NEUROIMAGING DATAK01MH104592 · NIMH · WASHINGTON UNIVERSITY · PI GREENE, DEANNA JACQUELYN · 2014 to 2018
$723k
Functional Circuits as an Endophenotype for ADHD in ChildrenR00MH091238 · NIMH · OREGON HEALTH & SCIENCE UNIVERSITY · PI FAIR, DAMIEN A · 2011 to 2013
$723k
Developing an Astroglial Model for Down SyndromeR21HD091512 · NICHD · RUTGERS, THE STATE UNIV OF N.J. · PI JIANG, PENG · 2017 to 2018
$426k
Precision Functional Mapping in Treatment-Resistant DepressionK99MH129616 · NIMH · WASHINGTON UNIVERSITY · PI LAUMANN, TIMOTHY OTTO · 2022 to 2023
$292k
Neurodevelopmental profiles related to transdiagnostic and disorder-specific symptoms of anxiety and depressionK99MH121518 · NIMH · WASHINGTON UNIVERSITY · PI MAREK, SCOTT · 2020 to 2021
$228k
NICHD NIH HHS P50 HD103538NICHD NIH HHS R01 HD057076NICHD NIH HHS R21 HD091512NIMH NIH HHS K01 MH104592NIMH NIH HHS K99 MH121518NIMH NIH HHS K99 MH129616NIMH NIH HHS R00 MH091238NIMH NIH HHS R00 MH121518NIMH NIH HHS R01 MH096773NIMH NIH HHS T32 MH100019
6 · The paper itself

Abstract

The thalamus is a critical relay center for neural pathways involving sensory, motor, and cognitive functions, including cortico-striato-thalamo-cortical and cortico-ponto-cerebello-thalamo-cortical loops. Despite the importance of these circuits, their development has been understudied. One way to investigate these pathways in human development in vivo is with functional connectivity MRI, yet few studies have examined thalamo-cortical and cerebello-cortical functional connectivity in development. Here, we used resting-state functional connectivity to measure functional connectivity in the thalamus and cerebellum with previously defined cortical functional networks in 2 separate data sets of children (7-12 years old) and adults (19-40 years old). In both data sets, we found stronger functional connectivity between the ventral thalamus and the somatomotor face cortical functional network in children compared with adults, extending previous cortico-striatal functional connectivity findings. In addition, there was more cortical network integration (i.e. strongest functional connectivity with multiple networks) in the thalamus in children than in adults. We found no developmental differences in cerebello-cortical functional connectivity. Together, these results suggest different maturation patterns in cortico-striato-thalamo-cortical and cortico-ponto-cerebellar-thalamo-cortical pathways.

Indexed as

CerebellumMagnetic Resonance ImagingAdultChildCorpus StriatumHumansNeural PathwaysThalamusYoung Adultbrain networkscerebellumfunctional MRIneurodevelopmentthalamus

Identifiers

PMID37293735
PMCPMC10492576

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.