ArticleBiomarkers in neuropsychiatry2020
Neurocognitive and neurophysiological endophenotypes in schizophrenia: An overview.
Article in Biomarkers in neuropsychiatry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.
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Who cites it
19 citing papers in PubMed, 1 synthesis or guideline pooled it.
- A Systematic Review to Explore a Neuropsychological Profile that Predates Anorexia Nervosa.Archives of clinical neuropsychology : the official journal of the National Academy of Neuropsychologists · 2025Pooled it
- Auditory event-related potentials and psychosis dimensions.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2026Article
- Genetic pathways linking oxytocin-vasotocin hypothalamic subunit architecture with psychiatric and metabolic traits.Molecular psychiatry · 2026Article
- Towards Mechanism-Informed Treatments for Mental Health.Journal of neurochemistry · 2026Review
- Cognitive Deficits in Schizophrenia: Brain Deorganization and Neurorehabilitation.Advances in experimental medicine and biology · 2026Review
- Schizophrenia endophenotypes: a review of neurophysiological, neuropsychological, and social cognition markers.Frontiers in psychiatry · 2026Review
- Effect of polygenic scores on the relationship between psychosis and cognition.Translational psychiatry · 2025Article
- Translating the Power of Precision Medicine Into the World of Communication Disorders.Journal of speech, language, and hearing research : JSLHR · 2025Review
- Multimodal evidence of mediodorsal thalamus-prefrontal circuit dysfunctions in clinical high-risk for psychosis: findings from a combined 7T fMRI, MRSI and sleep Hd-EEG study.Molecular psychiatry · 2025Article
- Associations Between Klotho Levels,Schizophrenia bulletin open · 2025Article
- An analysis of the clinical application of paliperidone palmitate injection based on real-world.Frontiers in pharmacology · 2025Article
- Whose Signals Are Being Amplified? Toward a More Equitable Clinical Psychophysiology.Clinical psychological science : a journal of the Association for Psychological Science · 2024Article
- Reduced slow wave density is associated with worse positive symptoms in clinical high risk: An objective readout of symptom severity for early treatment interventions?Psychiatry research · 2024Article
- Motion and Form Perception in Childhood-Onset Schizophrenia.Pediatric reports · 2024Article
- Natural Oscillatory Frequency Slowing in the Premotor Cortex of Early-Course Schizophrenia Patients: A TMS-EEG Study.Brain sciences · 2023Article
- Patients with Schizophrenia Showed Worse Cognitive Performance than Bipolar and Major Depressive Disorder in a Sample with Comorbid Substance Use Disorders.Journal of clinical medicine · 2022Article
- The positive dimension of schizotypy is associated with a reduced attenuation and precision of self-generated touch.Schizophrenia (Heidelberg, Germany) · 2022Article
- Subjective Cognitive Complaints in Unaffected First-Degree Relatives of Schizophrenia Patients: Relation to Cognitive Performance, Psychotic Experiences, and Social Functioning.Indian journal of psychological medicine · 2022Article
- Reduced readiness potential and post-movement beta synchronization reflect self-disorders in early course schizophrenia.Scientific reports · 2021Article
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Authors and funding
3 authors.
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Abstract
Schizophrenia (SCZ) is a severe psychotic disorder that affects up to 1% of the US population and it is associated with progressive impairment in social functioning and cognition. Nonetheless, despite its high burden, the pathophysiology of SCZ, including the genetic and biological mechanisms underlying the development and manifestation of the disorder, remains largely elusive. Endophenotypes are subtypes of biological markers that are more closely related to the genetic vulnerability for a disorder (e.g., SCZ). Recently, research on endophenotypes has identified several parameters that may prove useful in shedding light over the underlying neurobiology of SCZ. In this article, we provide an overview of the most established SCZ endophenotypes in the domains of neurocognition (attention deficits, working and verbal declarative memory dysfunctions) and neurophysiology (pre-pulse inhibition, anti-saccade impairment, event-related potential deficits) along with some novel, sleep-based measures (reduced sleep spindles and sleep slow waves). We also discuss recent conceptual advances in the field that may lead to novel, personalized treatment interventions for patients affected by this devastating mental illness.
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