Evidence map›Paper›PMID 37293342›Full record

ArticleRadiology. Artificial intelligence2023

Influence of Data Distribution on Federated Learning Performance in Tumor Segmentation.

Guibo Luo, Tianyu Liu, Jinghui Lu, Xin Chen, Lequan Yu, Jian Wu, Danny Z Chen, Wenli Cai

Abstract read
In one paragraph

Article in Radiology. Artificial intelligence, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Real-world federated learning in radiology: hurdles to overcome and benefits to gain.Journal of the American Medical Informatics Association : JAMIA · 2025
    Article
  6. Article
  7. Article
  8. The Role of Federated Learning Models in Medical Imaging.Radiology. Artificial intelligence · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Guibo LuoFrom the Department of Radiology, Massachusetts General Hospital and Harvard Medical School, 25 New Chardon St, 400C, Boston, MA 02114 (G.L., T.L., J.L., W.C.); Intel Corporation, Santa Clara, Calif (X.C.); Department of Statistics and Actuarial Science, The University of Hong Kong, Hong Kong (L.Y.); College of Computer Science and Technology, Zhejiang University, Hangzhou, China (J.W.); and Department of Computer Science and Engineering, University of Notre Dame, Notre Dame, Ind (D.Z.C.).ORCID https://orcid.org/0000-0002-1709-1207
Tianyu LiuFrom the Department of Radiology, Massachusetts General Hospital and Harvard Medical School, 25 New Chardon St, 400C, Boston, MA 02114 (G.L., T.L., J.L., W.C.); Intel Corporation, Santa Clara, Calif (X.C.); Department of Statistics and Actuarial Science, The University of Hong Kong, Hong Kong (L.Y.); College of Computer Science and Technology, Zhejiang University, Hangzhou, China (J.W.); and Department of Computer Science and Engineering, University of Notre Dame, Notre Dame, Ind (D.Z.C.).ORCID 0000-0002-1289-6380
Jinghui LuFrom the Department of Radiology, Massachusetts General Hospital and Harvard Medical School, 25 New Chardon St, 400C, Boston, MA 02114 (G.L., T.L., J.L., W.C.); Intel Corporation, Santa Clara, Calif (X.C.); Department of Statistics and Actuarial Science, The University of Hong Kong, Hong Kong (L.Y.); College of Computer Science and Technology, Zhejiang University, Hangzhou, China (J.W.); and Department of Computer Science and Engineering, University of Notre Dame, Notre Dame, Ind (D.Z.C.).
Xin ChenFrom the Department of Radiology, Massachusetts General Hospital and Harvard Medical School, 25 New Chardon St, 400C, Boston, MA 02114 (G.L., T.L., J.L., W.C.); Intel Corporation, Santa Clara, Calif (X.C.); Department of Statistics and Actuarial Science, The University of Hong Kong, Hong Kong (L.Y.); College of Computer Science and Technology, Zhejiang University, Hangzhou, China (J.W.); and Department of Computer Science and Engineering, University of Notre Dame, Notre Dame, Ind (D.Z.C.).ORCID 0000-0003-1950-2468
Lequan YuFrom the Department of Radiology, Massachusetts General Hospital and Harvard Medical School, 25 New Chardon St, 400C, Boston, MA 02114 (G.L., T.L., J.L., W.C.); Intel Corporation, Santa Clara, Calif (X.C.); Department of Statistics and Actuarial Science, The University of Hong Kong, Hong Kong (L.Y.); College of Computer Science and Technology, Zhejiang University, Hangzhou, China (J.W.); and Department of Computer Science and Engineering, University of Notre Dame, Notre Dame, Ind (D.Z.C.).ORCID 0000-0002-9315-6527
Jian WuFrom the Department of Radiology, Massachusetts General Hospital and Harvard Medical School, 25 New Chardon St, 400C, Boston, MA 02114 (G.L., T.L., J.L., W.C.); Intel Corporation, Santa Clara, Calif (X.C.); Department of Statistics and Actuarial Science, The University of Hong Kong, Hong Kong (L.Y.); College of Computer Science and Technology, Zhejiang University, Hangzhou, China (J.W.); and Department of Computer Science and Engineering, University of Notre Dame, Notre Dame, Ind (D.Z.C.).
Danny Z ChenFrom the Department of Radiology, Massachusetts General Hospital and Harvard Medical School, 25 New Chardon St, 400C, Boston, MA 02114 (G.L., T.L., J.L., W.C.); Intel Corporation, Santa Clara, Calif (X.C.); Department of Statistics and Actuarial Science, The University of Hong Kong, Hong Kong (L.Y.); College of Computer Science and Technology, Zhejiang University, Hangzhou, China (J.W.); and Department of Computer Science and Engineering, University of Notre Dame, Notre Dame, Ind (D.Z.C.).ORCID 0000-0001-6565-2884
Wenli CaiFrom the Department of Radiology, Massachusetts General Hospital and Harvard Medical School, 25 New Chardon St, 400C, Boston, MA 02114 (G.L., T.L., J.L., W.C.); Intel Corporation, Santa Clara, Calif (X.C.); Department of Statistics and Actuarial Science, The University of Hong Kong, Hong Kong (L.Y.); College of Computer Science and Technology, Zhejiang University, Hangzhou, China (J.W.); and Department of Computer Science and Engineering, University of Notre Dame, Notre Dame, Ind (D.Z.C.).ORCID 0000-0001-5883-5383

Funding

MDCT Quantification of hepatic tumor viability for assessment of cancer therapyR42CA189637 · NCI · IQ MEDICAL IMAGING, LLC · PI CAI, WENLI, WU, YIN · 2018 to 2019
$1.4M
NCI NIH HHS R42 CA189637
6 · The paper itself

Abstract

Purpose: To investigate the correlation between differences in data distributions and federated deep learning (Fed-DL) algorithm performance in tumor segmentation on CT and MR images. Materials and Methods: Two Fed-DL datasets were retrospectively collected (from November 2020 to December 2021): one dataset of liver tumor CT images (Federated Imaging in Liver Tumor Segmentation [or, FILTS]; three sites, 692 scans) and one publicly available dataset of brain tumor MR images (Federated Tumor Segmentation [or, FeTS]; 23 sites, 1251 scans). Scans from both datasets were grouped according to site, tumor type, tumor size, dataset size, and tumor intensity. To quantify differences in data distributions, the following four distance metrics were calculated: earth mover's distance (EMD), Bhattacharyya distance (BD), χ Results: The Dice coefficient ratio (θ) between federated and centralized models was strongly negatively correlated with the distances between data distributions, with correlation coefficients of -0.920 for EMD, -0.893 for BD, and -0.899 for CSD. However, KSD was weakly correlated with θ, with a correlation coefficient of -0.479. Conclusion: Performance of Fed-DL models in tumor segmentation on CT and MRI datasets was strongly negatively correlated with the distances between data distributions.

Indexed as

Abdomen/GIBrain/Brain StemComparative StudiesConvolutional Neural Network (CNN)CTData DistributionFederated Deep LearningLiverMR ImagingTumor Segmentation

Identifiers

PMID37293342
PMCPMC10245185

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.