Evidence map›Paper›PMID 37293276›Full record

ArticleFrontiers in cardiovascular medicine2023

Associations of adenovirus-reactive immunoglobulins with atrial fibrillation and body mass index.

Nadezhda G Gumanova, Polina D Zlobina, Natalya L Bogdanova, Hakob A Brutyan, Elena N Kalemberg, Victoria A Metelskaya, Karapet V Davtyan, Oksana M Drapkina

Open access · goldAbstract read
In one paragraph

Article in Frontiers in cardiovascular medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.3field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Nadezhda G GumanovaDepartment of Biochemistry, National Research Center for Preventive Medicine (NRCPM), Moscow, Russia.
Polina D ZlobinaDepartment of Biochemistry, National Research Center for Preventive Medicine (NRCPM), Moscow, Russia.
Natalya L BogdanovaDepartment of Biochemistry, National Research Center for Preventive Medicine (NRCPM), Moscow, Russia.
Hakob A BrutyanDepartment of Biochemistry, National Research Center for Preventive Medicine (NRCPM), Moscow, Russia.
Elena N KalembergDepartment of Biochemistry, National Research Center for Preventive Medicine (NRCPM), Moscow, Russia.
Victoria A MetelskayaDepartment of Biochemistry, National Research Center for Preventive Medicine (NRCPM), Moscow, Russia.
Karapet V DavtyanDepartment of Biochemistry, National Research Center for Preventive Medicine (NRCPM), Moscow, Russia.
Oksana M DrapkinaDepartment of Biochemistry, National Research Center for Preventive Medicine (NRCPM), Moscow, Russia.
National Research Center for Preventive Medicine · RU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Adenovirus (AdV) has been suggested to be involved in pathogenesis of atrial fibrillation (AF). We aimed to evaluate an association between AdV-specific immunoglobulins G in the serum (AdV-IgG) and AF. The present case-control study comprised two cohorts, including cohort 1 of patients with AF and cohort 2 of asymptomatic subjects. Initially, two groups, MA and MB, were selected from the cohorts 1 and 2, respectively, for serum proteome profiling using an antibody microarray to identify possible relevant protein targets. The data of microarray analysis indicated a possible overall increase in the total adenovirus signals in the group MA vs. group MB, suggesting potential relevance of adenoviral infection to AF. Then, the groups A (with AF) and B (control) were selected from the cohorts 1 and 2, respectively, to assay the presence and levels of AdV-IgG- by ELSA. The prevalence of AdV-IgG-positive status demonstrated a 2-fold increase in the group A (AF) compared with that in the group B (asymptomatic subjects); odds ratio 2.06 (95%CI: 1.11-3.84;

Indexed as

AdV-IgGantibody microarrayatrial fibrillationobesityserum

Identifiers

PMID37293276
PMCPMC10246773
OpenAlexW4378072342

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.