Evidence map›Paper›PMID 37293232›Full record

ReviewFrontiers in microbiology2023

Wastewater treatment plants, an "escape gate" for ESCAPE pathogens.

Luminita Gabriela Marutescu, Marcela Popa, Irina Gheorghe-Barbu, Ilda Czobor Barbu, Daloha Rodríguez-Molina, Fanny Berglund, Hetty Blaak, Carl-Fredrik Flach, Merel Aurora Kemper, Beate Spießberger and 10 more

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in microbiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed
7.5field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

35 citing papers in PubMed, 78 citations in OpenAlex.

  1. Article
  2. Genomic Surveillance of ESBL-ProducingPathogens (Basel, Switzerland) · 2026
    Article
  3. Article
  4. Review
  5. Review
  6. Article
  7. Article
  8. Review
  9. Tracking ESBL-ProducingVeterinary sciences · 2026
    Article
  10. Genetic diversity ofJournal of water and health · 2026
    Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors at 8 institutions in 4 countries.

Luminita Gabriela MarutescuDepartment of Microbiology and Immunology, Faculty of Biology, Research Institute of the University of Bucharest, University of Bucharest, Bucharest, Romania.
Marcela PopaEarth, Environmental and Life Sciences Section, Research Institute of the University of Bucharest, University of Bucharest, Bucharest, Romania.
Irina Gheorghe-BarbuDepartment of Microbiology and Immunology, Faculty of Biology, Research Institute of the University of Bucharest, University of Bucharest, Bucharest, Romania.
Ilda Czobor BarbuDepartment of Microbiology and Immunology, Faculty of Biology, Research Institute of the University of Bucharest, University of Bucharest, Bucharest, Romania.
Daloha Rodríguez-MolinaInstitute and Clinic for Occupational, Social and Environmental Medicine, University Hospital, LMU Munich, Munich, Germany.
Fanny BerglundDepartment of Infectious Diseases, Institute of Biomedicine, University of Gothenburg, Gothenburg, Sweden.
Hetty BlaakCentre for Infectious Disease Control, National Institute for Public Health and the Environment, Bilthoven, Netherlands.
Carl-Fredrik FlachDepartment of Infectious Diseases, Institute of Biomedicine, University of Gothenburg, Gothenburg, Sweden.
Merel Aurora KemperCentre for Infectious Disease Control, National Institute for Public Health and the Environment, Bilthoven, Netherlands.
Beate SpießbergerGerman Centre for Infection Research (DZIF), Partner Site Munich, Munich, Germany.
Laura WengenrothInstitute and Clinic for Occupational, Social and Environmental Medicine, University Hospital, LMU Munich, Munich, Germany.
D G Joakim LarssonDepartment of Infectious Diseases, Institute of Biomedicine, University of Gothenburg, Gothenburg, Sweden.
Dennis NowakInstitute and Clinic for Occupational, Social and Environmental Medicine, University Hospital, LMU Munich, Munich, Germany.
Katja RadonInstitute and Clinic for Occupational, Social and Environmental Medicine, University Hospital, LMU Munich, Munich, Germany.
Ana Maria de Roda HusmanCentre for Infectious Disease Control, National Institute for Public Health and the Environment, Bilthoven, Netherlands.
Andreas WieserGerman Centre for Infection Research (DZIF), Partner Site Munich, Munich, Germany.
Heike SchmittCentre for Infectious Disease Control, National Institute for Public Health and the Environment, Bilthoven, Netherlands.
Gratiela Pircalabioru GradisteanuDepartment of Microbiology and Immunology, Faculty of Biology, Research Institute of the University of Bucharest, University of Bucharest, Bucharest, Romania.
Corneliu Ovidiu VrancianuDepartment of Microbiology and Immunology, Faculty of Biology, Research Institute of the University of Bucharest, University of Bucharest, Bucharest, Romania.
Mariana Carmen ChifiriucDepartment of Microbiology and Immunology, Faculty of Biology, Research Institute of the University of Bucharest, University of Bucharest, Bucharest, Romania.
University of Bucharest · RONational Institute for Public Health and the Environment · NLLudwig-Maximilians-Universität München · DEUniversity of Gothenburg · SEGerman Center for Lung Research · DELMU Klinikum · DERomanian Academy · ROZimmer Biomet (Germany) · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Antibiotics are an essential tool of modern medicine, contributing to significantly decreasing mortality and morbidity rates from infectious diseases. However, persistent misuse of these drugs has accelerated the evolution of antibiotic resistance, negatively impacting clinical practice. The environment contributes to both the evolution and transmission of resistance. From all anthropically polluted aquatic environments, wastewater treatment plants (WWTPs) are probably the main reservoirs of resistant pathogens. They should be regarded as critical control points for preventing or reducing the release of antibiotics, antibiotic-resistant bacteria (ARB), and antibiotic-resistance genes (ARGs) into the natural environment. This review focuses on the fate of the pathogens

Indexed as

antibiotic resistanceantibiotic resistance genesESCAPE pathogensESCAPE species disseminationhigh-risk clonesmultidrug resistancewastewater treatment plants

Identifiers

PMID37293232
PMCPMC10244645
OpenAlexW4378072551

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.