ArticleFrontiers in microbiology2023
Characterization of the semen, gut, and urine microbiota in patients with different semen abnormalities.
Article in Frontiers in microbiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.
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Who cites it
23 citing papers in PubMed, 1 synthesis or guideline pooled it, 28 citations in OpenAlex.
- Is Lactobacillus spp. beneficial in human semen? Systematic review.JBRA assisted reproduction · 2025Pooled it
- The role of gut microbiome in aging-associated diseases: where do we stand now and how technology will transform the future.Gut microbes · 2026Review
- Unfolding the Semen Microbiota: Implications for Male Infertility.Biomedicines · 2026Review
- Seminal Plasma Microbiome Composition and Its Association with Sperm Morphology in Breeding Boars.Biology · 2026Article
- Gut-testis axis: how microbiota influence male reproductive health.Asian biomedicine : research, reviews and news · 2026Review
- Gut Microbial Dysbiosis and Male Reproductive Health: Current Insights and Future Directions.International journal of molecular sciences · 2026Review
- Gut microbiota and their role in male reproductive health.NPJ science of food · 2026Review
- Microbial Landscape of Bull (Animals : an open access journal from MDPI · 2026Article
- Effects of combined plant bioactives and probiotic supplementation on ram semen quality outside the breeding season.Open veterinary journal · 2026Article
- Probiotics as Microbiome Modulators in Male Infertility: Rethinking Dysbiosis Across the Gut-Testis Axis.Journal of personalized medicine · 2026Review
- The impact of vasectomy on the seminal microbiome: possible implications and source of microbes.Human reproduction open · 2026Article
- Interpretable machine learning uncovers core seminal microbial signatures in idiopathic oligoasthenospermia.Frontiers in cellular and infection microbiology · 2026Article
- Gut dysbiosis induces the development of asthenozoospermia through butanoate metabolism.Frontiers in immunology · 2026Article
- Evaluation of the semen microbiome for fertility in men with obesity using next-generation sequencing.Basic and clinical andrology · 2025Article
- The influence of seminal microbiota on human testicular steroidogenesis: a prospective study.Journal of assisted reproduction and genetics · 2025Article
- Non-Targeted Analysis of Environmental Contaminants and Their Associations with Semen Health Factors in Men from New York City.Environment & health (Washington, D.C.) · 2025Article
- Characterizing the seminal microbiota in mature rams managed on divergent planes of nutrition, and their male offspring.Journal of animal science · 2025Article
- Contribution of the seminal microbiome to paternal programming.Biology of reproduction · 2024Review
- Male Tract Microbiota and Male Infertility.Cells · 2024Review
- Tumour-associated and non-tumour-associated bacteria co-abundance groups in colorectal cancer.BMC microbiology · 2024Article
Corrections and comments
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Authors and funding
10 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Introduction: Semen quality is decreasing worldwide, leading to increased male infertility. This study analyzed the microbiota of the gut, semen, and urine in individuals with semen abnormalities to identify potential probiotics and pathogenic bacteria that affect semen parameters and help develop new methods for the diagnosis and treatment of patients with semen abnormalities. Methods: We recruited 12 individuals with normal semen parameters (control group), 12 with asthenospermia but no semen hyperviscosity (Group_1), 6 with oligospermia (Group_2), 9 with severe oligospermia or azoospermia (Group_3), and 14 with semen hyperviscosity only (Group_4). The semen, gut, and urine microbiota were examined by analyzing the 16S ribosomal RNA gene sequence using next-generation sequencing. Results: The gut microbes were clustered into the highest number of operational taxonomic units, followed by urine and semen. Furthermore, the α-diversity of gut microbes was highest and significantly different from that of urine and semen microbiota. The microbiota of the gut, urine, and semen were all significantly different from each other in terms of β-diversity. The gut abundance of Discussion: This study comprehensively describes the differences in intestinal and genitourinary tract microbiota between healthy individuals and those with abnormal semen parameters. Furthermore, our study identified
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.