Evidence map›Paper›PMID 37293144›Full record

ReviewAmerican journal of cancer research2023

Role of spasmolytic polypeptide-expressing metaplasia in gastric mucosal diseases.

Xi Liu, Zhiyuan Ma, Zilin Deng, Zhiqiang Yi, Biguang Tuo, Taolang Li, Xuemei Liu

Open access · greenAbstract readReview
In one paragraph

Review in American journal of cancer research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.9field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Recent advances in spasmolytic polypeptide expressing metaplasia research.World journal of gastrointestinal oncology · 2026
    Review
  3. Article
  4. Review
  5. Pyroptosis in gastric mucosal injury‑related diseases (Review).International journal of molecular medicine · 2025
    Review
  6. Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Xi LiuDepartment of Gastroenterology, Digestive Disease Hospital, Affiliated Hospital of Zunyi Medical University Zunyi, Guizhou, China.
Zhiyuan MaDepartment of Gastroenterology, Digestive Disease Hospital, Affiliated Hospital of Zunyi Medical University Zunyi, Guizhou, China.
Zilin DengDepartment of Gastroenterology, Digestive Disease Hospital, Affiliated Hospital of Zunyi Medical University Zunyi, Guizhou, China.
Zhiqiang YiDepartment of Gastroenterology, Digestive Disease Hospital, Affiliated Hospital of Zunyi Medical University Zunyi, Guizhou, China.
Biguang TuoDepartment of Gastroenterology, Digestive Disease Hospital, Affiliated Hospital of Zunyi Medical University Zunyi, Guizhou, China.
Taolang LiDepartment of General Surgery, Affiliated Hospital of Zunyi Medical University Zunyi, Guizhou, China.
Xuemei LiuDepartment of Gastroenterology, Digestive Disease Hospital, Affiliated Hospital of Zunyi Medical University Zunyi, Guizhou, China.
Zunyi Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Spasmolytic polypeptide-expressing metaplasia (SPEM) is a trefoil factor 2-expressing metaplasia in the fundic glands that resembles the fundic metaplasia of deep antral glandular cells and arises mainly from transdifferentiation of mature chief cells as well as mucous neck cells or isthmic stem cells. SPEM participates in the regulation of gastric mucosal injury, including focal and diffuse injury. This review focuses on the origin, models, and regulatory mechanisms of SPEM and on its role in the development of gastric mucosal injury. We hope to provide new prospects for the prevention and treatment of gastric mucosal diseases from the perspective of cell differentiation and transformation.

Indexed as

cellular differentiationdysplasiaGastric mucosal injurypreneoplastic metaplasiaregeneration and repair

Identifiers

PMID37293144
PMCPMC10244109
OpenAlexW4379967587

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.