Evidence map›Paper›PMID 37293139›Full record

ArticleEuropean heart journal open2023

Guideline-directed medical therapies for comorbidities among patients with atrial fibrillation: results from GARFIELD-AF.

Alan John Camm, Jan Steffel, Saverio Virdone, Jean-Pierre Bassand, Keith A A Fox, Samuel Z Goldhaber, Shinya Goto, Sylvia Haas, Alexander G G Turpie, Freek W A Verheugt and 6 more

Registry-linked trialAbstract read
In one paragraph

Article in European heart journal open, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01090362 (Prospective, Multi Centre, International Registry of Male and Female Patients Newly Diagnosed With Atrial Fibrillation.), which is not on this map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01090362 completednot on this map

Prospective, Multi Centre, International Registry of Male and Female Patients Newly Diagnosed With Atrial Fibrillation.

TypeobservationalSponsorThrombosis Research InstituteRan2009 to 2020Enrolled57,250ConditionsAtrial Fibrillation
3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Alan John CammCardiology Clinical Academic Group Molecular & Clinical Sciences Institute, St. George's University of London, London, UK.ORCID https://orcid.org/0000-0002-2536-2871
Jan SteffelUniversity of Zurich, Zurich, Switzerland.ORCID https://orcid.org/0000-0002-1477-9153
Saverio VirdoneThrombosis Research Institute, London, UK.ORCID https://orcid.org/0000-0003-1849-6422
Jean-Pierre BassandThrombosis Research Institute, London, UK.
Keith A A FoxCentre for Cardiovascular Science, University of Edinburgh, Edinburgh, UK.
Samuel Z GoldhaberBrigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.
Shinya GotoTokai University, Kanagawa, Japan.
Sylvia HaasFormerly Department of Medicine, Technical University of Munich, Munich, Germany.ORCID https://orcid.org/0000-0003-0837-7892
Alexander G G TurpieMcMaster University, Hamilton, Canada.
Freek W A VerheugtOnze Lieve Vrouwe Gasthuis (OLVG), Amsterdam, The Netherlands.
Frank MisselwitzActimed Therapeutics, Berkshire, UK.ORCID https://orcid.org/0000-0003-1366-7958
Ramón Corbalán HerrerosPontificia Universidad Católica de Chile, Santiago, Chile.
Gloria KayaniThrombosis Research Institute, London, UK.
Karen S PieperThrombosis Research Institute, London, UK.
Ajay K KakkarThrombosis Research Institute, London, UK.
GARFIELD-AF Investigators

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aims: This study aimed to identify relationships in recently diagnosed atrial fibrillation (AF) patients with respect to anticoagulation status, use of guideline-directed medical therapy (GDMT) for comorbid cardiovascular conditions (co-GDMT), and clinical outcomes. The Global Anticoagulant Registry in the FIELD (GARFIELD)-AF is a prospective, international registry of patients with recently diagnosed non-valvular AF at risk of stroke (NCT01090362). Methods and results: Guideline-directed medical therapy was defined according to the European Society of Cardiology guidelines. This study explored co-GDMT use in patients enrolled in GARFIELD-AF (March 2013-August 2016) with CHA Conclusion: In this large prospective, international registry on AF, comprehensive co-GDMT was associated with a lower risk of mortality in patients with AF and CHA Clinical Trial Registration: Clinical Trial Registration-URL: http://www.clinicaltrials.gov. Unique identifier: NCT01090362.

Indexed as

Atrial fibrillationComorbidityGARFIELD-AFGuideline-directed medical therapyMortalityOral anticoagulant

Identifiers

PMID37293139
PMCPMC10246824

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.