ArticlebioRxiv : the preprint server for biology2023
Structural basis of TFIIIC-dependent RNA Polymerase III transcription initiation.
Anna Talyzina, Yan Han, Chiranjib Banerjee, Susan Fishbain, Alexis Reyes, Reza Vafabakhsh, Yuan He
Open access · greenAbstract readPreprint
In one paragraphArticle in bioRxiv : the preprint server for biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from itWhat it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literatureWho cites it
0 citing papers in PubMed, 1 citations in OpenAlex.
No citing paper in PubMed yet.
4 · The recordCorrections and comments
5 · Who and what moneyAuthors and funding
7 authors at 1 institution in 1 country.
Anna TalyzinaDepartment of Molecular Biosciences, Northwestern University, Evanston, IL, United States.
Yan HanDepartment of Molecular Biosciences, Northwestern University, Evanston, IL, United States.
Chiranjib BanerjeeDepartment of Molecular Biosciences, Northwestern University, Evanston, IL, United States.
Susan FishbainDepartment of Molecular Biosciences, Northwestern University, Evanston, IL, United States.
Alexis ReyesDepartment of Molecular Biosciences, Northwestern University, Evanston, IL, United States.
Reza VafabakhshDepartment of Molecular Biosciences, Northwestern University, Evanston, IL, United States.
Yuan HeDepartment of Molecular Biosciences, Northwestern University, Evanston, IL, United States.
Northwestern University · US
Funding
Tumor Environment and Metastasis (TEAM) Research ProgramP30CA060553 · NCI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI LEONIDAS C. PLATANIAS · 1993 to 2026
$153.9MTranscription-Coupled & Replication-Associated Excision RepairP01CA092584 · NCI · UNIVERSITY OF CALIF-LAWRENC BERKELEY LAB · PI WALTER J. CHAZIN · 2001 to 2026
$89.6MPacific Northwest Center for Cryo-EM - Screening supplementU24GM129547 · NIGMS · OREGON HEALTH & SCIENCE UNIVERSITY · PI EVANS, JAMES E, GOUAUX, JAMES E · 2018 to 2023
$54.8MMolecular Biophysics Training Program at Northwestern UniversityT32GM140995 · NIGMS · NORTHWESTERN UNIVERSITY · PI Heather Wendy Pinkett, Reza Vafabakhsh · 2021 to 2026
$2.5MStructure and Mechanism of Non-Homologous End JoiningR01GM135651 · NIGMS · NORTHWESTERN UNIVERSITY · PI HE, YUAN · 2020 to 2024
$1.8MQuantitative analysis of metabotropic glutamate receptor activation and modulationR01GM140272 · NIGMS · NORTHWESTERN UNIVERSITY · PI VAFABAKHSH, REZA · 2020 to 2024
$1.7MStructure and Mechanism of Eukaryotic Transcription RegulationR01GM144559 · NIGMS · NORTHWESTERN UNIVERSITY · PI HE, YUAN · 2022 to 2025
$1.4MNCI NIH HHS P01 CA092584NCI NIH HHS P30 CA060553NIGMS NIH HHS R01 GM135651NIGMS NIH HHS R01 GM140272NIGMS NIH HHS R01 GM144559NIGMS NIH HHS T32 GM140995NIGMS NIH HHS U24 GM129547
6 · The paper itselfAbstract
RNA Polymerase III (Pol III) is responsible for transcribing 5S ribosomal RNA (5S rRNA), tRNAs, and other short non-coding RNAs. Its recruitment to the 5S rRNA promoter requires transcription factors TFIIIA, TFIIIC, and TFIIIB. Here we use cryo-electron microscopy to visualize the
Identifiers
PMID37292922
PMCPMC10245719
OpenAlexW4376876445
What OpenQuestion holds
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LicenceCC BY-NC-ND
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