Evidence map›Paper›PMID 37292901›Full record

ArticlebioRxiv : the preprint server for biology2023

Infection-induced epilepsy is caused by increased expression of chondroitin sulfate proteoglycans in hippocampus and amygdala.

Dipan C Patel, Nathaniel Swift, Bhanu P Tewari, Jack L Browning, Courtney Prim, Lata Chaunsali, Ian Kimbrough, Michelle L Olsen, Harald Sontheimer

Open access · greenAbstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Dipan C PatelDepartment of Neuroscience, School of Medicine, University of Virginia, Charlottesville, VA 22903, USA.
Nathaniel SwiftDepartment of Internal Medicine, Gerontology and Geriatric Medicine, School of Medicine, Wake Forest University, Winston-Salem, NC 27157, USA.
Bhanu P TewariDepartment of Neuroscience, School of Medicine, University of Virginia, Charlottesville, VA 22903, USA.
Jack L BrowningSchool of Neuroscience, Virginia Polytechnic Institute and State University, Blacksburg, VA 24061, USA.
Courtney PrimDepartment of Neuroscience, School of Medicine, University of Virginia, Charlottesville, VA 22903, USA.
Lata ChaunsaliDepartment of Neuroscience, School of Medicine, University of Virginia, Charlottesville, VA 22903, USA.
Ian KimbroughDepartment of Neuroscience, School of Medicine, University of Virginia, Charlottesville, VA 22903, USA.
Michelle L OlsenSchool of Neuroscience, Virginia Polytechnic Institute and State University, Blacksburg, VA 24061, USA.
Harald SontheimerDepartment of Neuroscience, School of Medicine, University of Virginia, Charlottesville, VA 22903, USA.
University of Virginia · USVirginia Tech · USWake Forest University · US

Funding

The Role of Ion Transport in Glioma Migration, Proliferation, and ApoptosisR01NS036692 · NINDS · VIRGINIA POLYTECHNIC INST AND ST UNIV · PI SONTHEIMER, HARALD W · 1997 to 2024
$6.8M
Amino Acid Transport and the Biology of Human GliomasR01NS052634 · NINDS · VIRGINIA POLYTECHNIC INST AND ST UNIV · PI SONTHEIMER, HARALD W · 2005 to 2015
$3.7M
Glioma-Astrocyte Vascular InteractionsR01NS082851 · NINDS · VIRGINIA POLYTECHNIC INST AND ST UNIV · PI SONTHEIMER, HARALD W · 2013 to 2016
$1.3M
NINDS NIH HHS R01 NS036692NINDS NIH HHS R01 NS052634NINDS NIH HHS R01 NS082851
6 · The paper itself

Abstract

Alterations in the extracellular matrix (ECM) are common in epilepsy, yet whether they are cause or consequence of disease is unknow. Using Theiler's virus infection model of acquired epilepsy we find

Identifiers

PMID37292901
PMCPMC10245664
OpenAlexW4377027435

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.