ArticlebioRxiv : the preprint server for biology2023
An evolutionary mechanism to assimilate new nutrient sensors into the mTORC1 pathway.
Grace Y Liu, Patrick Jouandin, Raymond E Bahng, Norbert Perrimon, David M Sabatini
Abstract readPreprint
In one paragraphArticle in bioRxiv : the preprint server for biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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0citing papers in PubMed
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
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3 · Its place in the literatureWho cites it
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4 · The recordCorrections and comments
5 · Who and what moneyAuthors and funding
5 authors.
Grace Y LiuWhitehead Institute for Biomedical Research and Massachusetts Institute of Technology, Department of Biology; 455 Main Street, Cambridge, Massachusetts 02142, USA.
Patrick JouandinDepartment of Genetics, Blavatnik Institute, Harvard Medical School; Boston, MA 02115, USA.
Raymond E BahngWhitehead Institute for Biomedical Research and Massachusetts Institute of Technology, Department of Biology; 455 Main Street, Cambridge, Massachusetts 02142, USA.
Norbert PerrimonDepartment of Genetics, Blavatnik Institute, Harvard Medical School; Boston, MA 02115, USA.
David M SabatiniWhitehead Institute for Biomedical Research and Massachusetts Institute of Technology, Department of Biology; 455 Main Street, Cambridge, Massachusetts 02142, USA.
Funding
PRE-DOCTORAL TRAINING IN THE BIOLOGICAL SCIENCEST32GM007287 · NIGMS · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · PI BELL, STEPHEN P., KEATING, AMY E · 1985 to 2019
$40.8MTuberous Sclerosis-Pathway and PathogenesisP01CA120964 · NCI · BRIGHAM AND WOMEN'S HOSPITAL · PI David J. Kwiatkowski · 2007 to 2026
$35.9MCharacterization of the Insulin to Autophagy Pathway in MusclesR01AR057352 · NIAMS · HARVARD MEDICAL SCHOOL · PI NORBERT PERRIMON · 2010 to 2026
$8.2MRegulation of the mTOR Pathway By NutrientsR01CA103866 · NCI · WHITEHEAD INSTITUTE FOR BIOMEDICAL RES · PI WEISSMAN, JONATHAN S. · 2004 to 2021
$7.0MCell Growth Signaling in Cancer DevelopmentR01CA129105 · NCI · WHITEHEAD INSTITUTE FOR BIOMEDICAL RES · PI WEISSMAN, JONATHAN S. · 2008 to 2021
$5.9MTRANSLATIONAL CONTROL BY RAPAMYCIN-SENSITIVE SIGNALINGR01AI047389 · NIAID · WHITEHEAD INSTITUTE FOR BIOMEDICAL RES · PI WEISSMAN, JONATHAN S. · 2000 to 2021
$4.9MDetermining the mechanism of serine sensing by the mTOR pathwayF31CA232340 · NCI · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · PI LIU, GRACE YUN · 2018 to 2021
$181kNCI NIH HHS F31 CA232340NCI NIH HHS P01 CA120964NCI NIH HHS R01 CA103866NCI NIH HHS R01 CA129105NIAID NIH HHS R01 AI047389NIAMS NIH HHS R01 AR057352NIGMS NIH HHS T32 GM007287
6 · The paper itselfAbstract
Animals must sense and respond to nutrient availability in their local niche. This task is coordinated in part by the mTOR complex 1 (mTORC1) pathway, which regulates growth and metabolism in response to nutrients
Identifiers
PMID37292894
PMCPMC10245982
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