Evidence map›Paper›PMID 37292788›Full record

ArticleResearch square2023

Higher Neuronal Facilitation and Potentiation with APOE4 Suppressed by Angiotensin II.

Sarah B Scheinman, Kuei Y Tseng, Simon Alford, Leon M Tai

Open access · greenAbstract readPreprint
In one paragraph

Article in Research square, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Sarah B ScheinmanUniversity of Illinois at Chicago College of Medicine.
Kuei Y TsengUniversity of Illinois at Chicago College of Medicine.
Simon AlfordUniversity of Illinois at Chicago College of Medicine.
Leon M TaiUniversity of Illinois at Chicago College of Medicine.ORCID 0000-0003-4430-6717
University of Illinois Chicago · US

Funding

Monoaminergic regulation of prefrontal cortex inhibition during adolescenceR01MH086507 · NIMH · UNIVERSITY OF ILLINOIS AT CHICAGO · PI Kuei-Yuan Tseng · 2010 to 2026
$5.7M
Deciphering molecular mechanisms that underlie brain endothelial cell dysfunction with APOE4R01AG061114 · NIA · UNIVERSITY OF ILLINOIS AT CHICAGO · PI Leon Maing Tai · 2019 to 2026
$4.7M
NIA NIH HHS R01 AG061114NIMH NIH HHS R01 MH086507
6 · The paper itself

Abstract

Progressive hippocampal degeneration is a key component of Alzheimer's disease (AD) progression. Therefore, identifying how hippocampal neuronal function is modulated early in AD is an important approach to eventually prevent degeneration. AD-risk factors and signaling molecules likely modulate neuronal function, including

Identifiers

PMID37292788
PMCPMC10246245
OpenAlexW4378363348

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.