ArticlebioRxiv : the preprint server for biology2024
Spatial Multiomics Reveal the Role of Wnt Modulator, Dkk2, in Palatogenesis.
Jeremie Oliver Piña, Resmi Raju, Daniela M Roth, Emma Wentworth Winchester, Cameron Padilla, James Iben, Fabio R Faucz, Justin L Cotney, Rena N D'Souza
Open access · greenAbstract readPreprint
In one paragraphArticle in bioRxiv : the preprint server for biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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0citing papers in PubMed
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What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
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3 · Its place in the literatureWho cites it
0 citing papers in PubMed, 1 citations in OpenAlex.
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4 · The recordCorrections and comments
5 · Who and what moneyAuthors and funding
9 authors at 2 institutions in 1 country.
Jeremie Oliver PiñaSection on Craniofacial Genetic Disorders, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD, USA.ORCID 0000-0003-3387-5770 Resmi RajuSection on Craniofacial Genetic Disorders, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD, USA.ORCID 0000-0002-5617-1269 Daniela M RothSection on Craniofacial Genetic Disorders, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD, USA.ORCID 0000-0001-8156-4681 Cameron PadillaMolecular Genomics Core, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD, USA.
James IbenMolecular Genomics Core, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD, USA.ORCID 0000-0002-1130-7660 Fabio R FauczMolecular Genomics Core, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD, USA.ORCID 0000-0001-7959-9842 Justin L CotneyDepartment of Genetics and Genome Sciences, University of Connecticut School of Medicine, Farmington, CT, USA.ORCID 0000-0001-8230-2157 Rena N D'SouzaSection on Craniofacial Genetic Disorders, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD, USA.ORCID 0000-0002-1505-5173 National Institutes of Health · USUniversity of Connecticut · US
Funding
Unraveling mechanisms of genome regulation to understand and improvehuman healthR35GM119465 · NIGMS · UNIVERSITY OF CONNECTICUT SCH OF MED/DNT · PI COTNEY, JUSTIN LEE · 2016 to 2025
$3.9MFunctional characterization of craniofacial enhancers at single cell and single base pair resolutionR01DE028945 · NIDCR · UNIVERSITY OF CONNECTICUT SCH OF MED/DNT · PI COTNEY, JUSTIN LEE · 2019 to 2023
$1.9MIntegrated multi-omics analyses of early mammalian craniofacial developmentR03DE028588 · NIDCR · UNIVERSITY OF CONNECTICUT SCH OF MED/DNT · PI COTNEY, JUSTIN LEE · 2020 to 2021
$328kUncovering Caries Risk in the Noncoding Genome of the Developing ToothF30DE031149 · NIDCR · UNIVERSITY OF CONNECTICUT SCH OF MED/DNT · PI WINCHESTER, EMMA WENTWORTH · 2021 to 2023
$139kIntramural NIH HHS ZIA HD009015NIDCR NIH HHS F30 DE031149NIDCR NIH HHS R01 DE028945NIDCR NIH HHS R03 DE028588NIGMS NIH HHS R35 GM119465
6 · The paper itselfAbstract
Multiple genetic and environmental etiologies contribute to the pathogenesis of cleft palate, which constitutes the most common among the inherited disorders of the craniofacial complex. Insights into the molecular mechanisms regulating osteogenic differentiation and patterning in the palate during embryogenesis are limited and needed for the development of innovative diagnostics and cures. This study utilized the
Indexed as
Cleft PalateCraniofacial AnomaliesCraniofacial Biology/GeneticsGene ExpressionSignal TransductionSingle Cell Sequencing
Identifiers
PMID37292772
PMCPMC10245699
OpenAlexW4376866483
What OpenQuestion holds
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LicenceCC BY-ND
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