Evidence map›Paper›PMID 37292740›Full record

ArticlebioRxiv : the preprint server for biology2023

Cytosolic iron-sulfur protein assembly system identifies clients by a C-terminal tripeptide.

Melissa D Marquez, Carina Greth, Anastasiya Buzuk, Yaxi Liu, Catharina M Blinn, Simone Beller, Laura Leiskau, Anthony Hushka, Kassandra Wu, Kübra Nur and 3 more

Open access · greenAbstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 2 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

13 authors at 2 institutions in 2 countries.

Melissa D MarquezDepartment of Chemistry, Boston University; Boston, MA, USA.
Carina GrethDepartment of Chemistry, RPTU Kaiserslautern-Landau; 67663 Kaiserslautern, Germany.
Anastasiya BuzukDepartment of Chemistry, Boston University; Boston, MA, USA.
Yaxi LiuDepartment of Chemistry, Boston University; Boston, MA, USA.
Catharina M BlinnDepartment of Chemistry, RPTU Kaiserslautern-Landau; 67663 Kaiserslautern, Germany.
Simone BellerDepartment of Chemistry, RPTU Kaiserslautern-Landau; 67663 Kaiserslautern, Germany.
Laura LeiskauDepartment of Chemistry, RPTU Kaiserslautern-Landau; 67663 Kaiserslautern, Germany.
Anthony HushkaDepartment of Chemistry, Boston University; Boston, MA, USA.
Kassandra WuDepartment of Chemistry, Boston University; Boston, MA, USA.
Kübra NurDepartment of Chemistry, RPTU Kaiserslautern-Landau; 67663 Kaiserslautern, Germany.
Daili J NetzDepartment of Chemistry, RPTU Kaiserslautern-Landau; 67663 Kaiserslautern, Germany.
Deborah L PerlsteinDepartment of Chemistry, Boston University; Boston, MA, USA.
Antonio J PierikDepartment of Chemistry, RPTU Kaiserslautern-Landau; 67663 Kaiserslautern, Germany.
University of Kaiserslautern · DEBoston University · US

Funding

The mechanism of apo-target recognition in cytsolic iron sulfur cluster biosynthesisR01GM121673 · NIGMS · BOSTON UNIVERSITY (CHARLES RIVER CAMPUS) · PI PERLSTEIN, DEBORAH L · 2018 to 2022
$1.6M
NIGMS NIH HHS R01 GM121673
6 · The paper itself

Abstract

The eukaryotic cytosolic Fe-S protein assembly (CIA) machinery inserts iron-sulfur (Fe-S) clusters into cytosolic and nuclear proteins. In the final maturation step, the Fe-S cluster is transferred to the apo-proteins by the CIA-targeting complex (CTC). However, the molecular recognition determinants of client proteins are unknown. We show that a conserved [LIM]-[DES]-[WF]-COO

Identifiers

PMID37292740
PMCPMC10245660
OpenAlexW4377142480

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.