Evidence map›Paper›PMID 37292496›Full record

ArticleEuropean urology open science2023

Jan Vanwelkenhuyzen, Eva Van Bos, Siska Van Bruwaene, Karl Lesage, Alex Maes, Sezgin Üstmert, Filip Lavent, Laurence Beels, Henrik Grönberg, Piet Ost and 2 more

Open access · goldAbstract read
In one paragraph

Article in European urology open science, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 1 pooled it
6.2field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 1 synthesis or guideline pooled it, 24 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Observational
  4. Variable cellular and radiobiological effects of [Journal of experimental & clinical cancer research : CR · 2026
    Article
  5. Article
  6. Liquid Biopsy of Circulating Tumor Cells and DNA in the Context of PSMA Radiopharmaceutical Therapy.Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2026
    Article
  7. Review
  8. Observational
  9. Article
  10. Review
  11. Review
  12. Study of predictive factors for response toFrontiers in medicine · 2025
    Article
  13. Review
  14. Review
  15. Review
  16. Article
  17. Initial Experience with [Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2024
    Article
  18. Article
  19. Impact ofTheranostics · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 2 countries.

Jan VanwelkenhuyzenDepartment of Human Structure and Repair, Ghent University, Ghent, Belgium.
Eva Van BosDepartment of Urology, AZ Groeninge, Kortrijk, Belgium.
Siska Van BruwaeneDepartment of Urology, AZ Groeninge, Kortrijk, Belgium.
Karl LesageDepartment of Urology, AZ Groeninge, Kortrijk, Belgium.
Alex MaesDepartment of Nuclear Medicine, AZ Groeninge, Kortrijk, Belgium.
Sezgin ÜstmertDepartment of Nuclear Medicine, AZ Groeninge, Kortrijk, Belgium.
Filip LaventDepartment of Nuclear Medicine, AZ Groeninge, Kortrijk, Belgium.
Laurence BeelsDepartment of Nuclear Medicine, AZ Groeninge, Kortrijk, Belgium.
Henrik GrönbergDepartment of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.
Piet OstDepartment of Human Structure and Repair, Ghent University, Ghent, Belgium.
Johan LindbergDepartment of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.
Bram De LaereDepartment of Human Structure and Repair, Ghent University, Ghent, Belgium.
AZ Groeninge · BEKarolinska Institutet · SEGhent University · BE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Lutetium-177 prostate-specific membrane antigen radioligands ( Patient summary: We examined cell-free DNA in blood samples from patients with advanced metastatic prostate cancer who started treatment with lutetium-177-PSMA, a new radioligand therapy. We found that patients with genetic alterations in the androgen receptor gene or PI3K pathway genes did not experience a lasting benefit from lutetium-177-PSMA.

Indexed as

BiomarkerCell-free DNACirculating tumour DNALiquid biopsyLutetium-177-PSMAMetastatic castration-resistant prostate cancer

Identifiers

PMID37292496
PMCPMC10244905
OpenAlexW4379196869

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.