Evidence map›Paper›PMID 37292400›Full record

ArticleSurgical neurology international2023

The efficacy of postoperative middle meningeal artery embolization on chronic subdural hematoma - A multicentered randomized controlled trial.

Alexander Lam, Denesh Selvarajah, Soe San Htike, Sophia Chan, Shivendra Lalloo, Gregory Lock, Kendal Redmond, David Leggett, Peter Mews

Registry-linked trialAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Surgical neurology international, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07633067 (Safety and Efficacy of Middle Meningeal Artery Embolization for the Treatment of Migraine), which is not on this map. Cited by 18 papers, 11 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 11 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07633067 nanot yet recruitingnot on this mapstarted 2026, after this paper: background citation

Safety and Efficacy of Middle Meningeal Artery Embolization for the Treatment of Migraine: A Multicenter, Prospective, Double-blind, Multigroup, Randomized Controlled Trial.

TypeinterventionalSponsorThe Affiliated Hospital Of Guizhou Medical UniversityRan2026 to 2028Enrolled150ConditionsMigraineArmsMiddle meningeal artery embolization, Conventional standard pharmacotherapy for migraine
3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 11 syntheses or guidelines pooled it.

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  15. N-butyl Cyanoacrylate Use in Various Neuroendovascular Diseases.Journal of neuroendovascular therapy · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Alexander LamDepartment of Neurosurgery, Princess Alexandra Hospital, Woolloongabba, Australia.
Denesh SelvarajahDepartment of Neurosurgery, Canberra Hospital, Garran, Australia.
Soe San HtikeDepartment of Neurosurgery, Princess Alexandra Hospital, Woolloongabba, Australia.
Sophia ChanDepartment of Neurosurgery, Princess Alexandra Hospital, Woolloongabba, Australia.
Shivendra LallooDepartment of Radiology, Canberra Hospital, Garran, Australia.
Gregory LockDepartment of Radiology, Princess Alexandra Hospital, Woolloongabba, Australia.
Kendal RedmondDepartment of Radiology, Princess Alexandra Hospital, Woolloongabba, Australia.
David LeggettDepartment of Radiology, Princess Alexandra Hospital, Woolloongabba, Australia.
Peter MewsDepartment of Neurosurgery, Canberra Hospital, Garran, Australia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Middle meningeal artery (MMA) embolization has recently emerged as a potential treatment for chronic subdural hematoma (cSDH). Numerous retrospective studies have suggested that it can potentially reduce the risk of hematoma recurrence following surgical evacuation. We have conducted a randomized controlled trial to investigate the effectiveness of postoperative MMA embolization in reducing recurrence rate, residual hematoma thickness as well as improving functional outcome. Methods: Patients aged 18 or above were recruited. Following evacuation through burr hole or craniotomy, patients were randomly allocated to undergo either MMA embolization or standard care (monitoring). The primary outcome was symptomatic recurrence requiring redo evacuation. Secondary outcomes include residual hematoma thickness and modified Rankin Scale (mRS) at 6 weeks and 3 months. Results: Thirty-six patients (41 cSDHs) were recruited between April 2021 and September 2022. Seventeen patients (19 cSDHs) were allocated to the embolization group and 19 patients (22 cSDHs) were in the control group. No symptomatic recurrence was observed in the treatment group while 3 control patients (15.8%) underwent repeat surgery for symptomatic recurrence, however, it was not statistically significant ( Conclusion: Further study with larger sample size is required to evaluate the efficacy of MMA embolization.

Indexed as

Chronic subdural hematomaInterventional neuroradiologyMiddle meningeal artery embolization

Identifiers

PMID37292400
PMCPMC10246309

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.