Evidence map›Paper›PMID 37292139›Full record

Article3 Biotech2023

Prevention of aspirin-mediated secondary toxicity by combined treatment of carotenoids in macrophages.

Kariyappa Vijay, Rudrappa Ambedkar, Poorigali Raghavendra-Rao Sowmya, Suresh Ramaiah, Ambati Ranga Rao, Rohit Gundamaraju, Manjunatha Hanumanthappa, M B Malarvili, Rishya Manikam, Rangaswamy Lakshminarayana

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in 3 Biotech, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.5field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 2 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 3 countries.

Kariyappa VijayDepartment of Microbiology and Biotechnology, Jnana Bharathi Campus, Bangalore University, Bangalore, 560 056 India.
Rudrappa AmbedkarDepartment of Microbiology and Biotechnology, Jnana Bharathi Campus, Bangalore University, Bangalore, 560 056 India.
Poorigali Raghavendra-Rao SowmyaDepartment of Microbiology and Biotechnology, Jnana Bharathi Campus, Bangalore University, Bangalore, 560 056 India.
Suresh RamaiahDepartment of Statistics, Jnana Bharathi Campus, Bangalore University, Bangalore, 560 056 India.
Ambati Ranga RaoDepartment of Biotechnology, Vignan's Foundation of Science, Technology and Research (Deemed to be University), Vadlamudi, Guntur, Andhra Pradesh 522213 India.
Rohit GundamarajuER Stress and Mucosal Immunology Lab, School of Health Sciences, University of Tasmania, Launceston, TAS 7248 Australia.
Manjunatha HanumanthappaDepartment of Biochemistry, Jnana Bharathi Campus, Bangalore University, Bangalore, 560 056 India.
M B MalarviliTrauma and Emergency, University of Malaya, Kuala Lumpur, Malaysia.
Rishya ManikamSchool of Biomedical and Health Science, Universiti Teknologi Malaysia, 81310 Skudai, Johor Bahru Malaysia.
Rangaswamy LakshminarayanaDepartment of Microbiology and Biotechnology, Jnana Bharathi Campus, Bangalore University, Bangalore, 560 056 India.ORCID 0000-0002-6333-9795
Bangalore University · INUniversity of Malaya · MYUniversity of Tasmania · AUUniversity of Technology Malaysia · MYVignan's Foundation for Science, Technology & Research · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Upon understanding the boosting role of carotenoids on the endogenous anti-inflammatory system, it is vital to explore their role in reducing the use of high doses of non-steroidal anti-inflammatory drug (NSAIDs), and their mediated secondary toxicity during the treatment of chronic diseases. The current study investigates the carotenoids potential on inhibition of secondary complications induced by NSAIDs, aspirin (ASA) against lipopolysaccharide (LPS) stimulated inflammation. Initially, this study evaluated a minimal cytotoxic dose of ASA and carotenoids ( Supplementary Information: The online version contains supplementary material available at 10.1007/s13205-023-03632-w.

Indexed as

AspirinCarotenoidsMacrophagesReactive oxygen speciesSecondary toxicity

Identifiers

PMID37292139
PMCPMC10244315
OpenAlexW4379512155

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.