Evidence map›Paper›PMID 37292067›Full record

ArticleIndian journal of endocrinology and metabolism

Correlation of Serum FSH and Rate of Testicular Sperm Retrieval in Non-Obstructive Azoospermia.

Kaberi Banerjee, Bhavana Singla, Kiran Agria

Abstract read
In one paragraph

Article in Indian journal of endocrinology and metabolism. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

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4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Kaberi BanerjeeMedical Director, Department of Reproductive Medicine, Advance Fertililty and Gynaecology Center, New Delhi, India.
Bhavana SinglaSenior Consultant, Department of Reproductive Medicine, Advance Fertililty and Gynaecology Center, New Delhi, India.
Kiran AgriaEmbryologist, Department of Reproductive Medicine, Advance Fertililty and Gynaecology Center, New Delhi, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Sperm retrieval from men with azoospermia has evolved in recent times, providing patient hope for fulfilling their dream of having their own genetic child through testicular sperm extraction followed by intracytoplasmic sperm injection (TESE-ICSI). In the present study, we are correlating the serum follicle stimulating hormone (FSH) levels and the rate of testicular sperm retrieval. Aim: To correlate the serum FSH levels with surgically retrieved sperms from testes in non-obstructive azoospermia. Method: Sixty-six men presenting with male infertility, diagnosed with non-obstructive azoospermia based on standard guidelines were included in the study. The surgically retrieved tissue was washed in 4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid (HEPES) gamete buffer media and scanned under an inverted microscope at ×400. Outcome analysis was assessed through sperm retrieval rate. Result: Testicular sperms were successfully retrieved in 62% (41/66) of men. Sperm retrieval rate (SRR) with FSH values (Group A <10, Group B 10-20 and Group C >20) mIU/mL were 84% (26/31), 75% (12/16) and 15% (3/19), respectively. Conclusion: Chances of sperm retrieval in non-obstructive azoospermia using surgically retrieved sperm are as common for men with FSH levels <10 mIU/mL with 84% (26/31) retrieval as for the borderline 10-20 mIU/mL FSH levels with 75% (12/16) retrieval. We do have retrieved sperms with >20 IU/mL serum FSH also which is not a contradiction for TESE for such patients; however, such patient's need to be counselled about the chances of successful sperm retrieval and the consequent pregnancy outcomes.

Indexed as

AzoospermiaFSHnonobstructiveretrievalsperm

Identifiers

PMID37292067
PMCPMC10245302

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