Evidence map›Paper›PMID 37292057›Full record

ArticleRSC chemical biology2023

Radiolabeling and

Kirsten E Martin, Joseph A Mattocks, Dariusz Śmiłowicz, Eduardo Aluicio-Sarduy, Jennifer N Whetter, Jonathan W Engle, Joseph A Cotruvo, Eszter Boros

Erratum issuedOpen access · goldAbstract read
In one paragraph

Article in RSC chemical biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.1field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Preclinical evaluation of [Scientific reports · 2025
    Article
  3. Article
  4. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Kirsten E MartinDepartment of Chemistry, Stony Brook University, Stony Brook New York 11794 USA eszter.boros@stonybrook.edu.
Joseph A MattocksDepartment of Chemistry, The Pennsylvania State University, University Park Pennsylvania 16802 USA juc96@psu.edu.ORCID https://orcid.org/0000-0003-1541-0187
Dariusz ŚmiłowiczDepartment of Chemistry, Stony Brook University, Stony Brook New York 11794 USA eszter.boros@stonybrook.edu.
Eduardo Aluicio-SarduyDepartment of Medical Physics, University of Wisconsin Madison Wisconsin 53705 USA.
Jennifer N WhetterDepartment of Chemistry, Stony Brook University, Stony Brook New York 11794 USA eszter.boros@stonybrook.edu.
Jonathan W EngleDepartment of Medical Physics, University of Wisconsin Madison Wisconsin 53705 USA.
Joseph A CotruvoDepartment of Chemistry, The Pennsylvania State University, University Park Pennsylvania 16802 USA juc96@psu.edu.ORCID https://orcid.org/0000-0003-4243-8257
Eszter BorosDepartment of Chemistry, Stony Brook University, Stony Brook New York 11794 USA eszter.boros@stonybrook.edu.ORCID https://orcid.org/0000-0002-4186-6586
Stony Brook University · USPennsylvania State University · USUniversity of Wisconsin–Madison · US

Funding

Chemical Biology Training InterfaceT32GM136572 · NIGMS · STATE UNIVERSITY NEW YORK STONY BROOK · PI ELIZABETH M BOON, Jessica Chuang Seeliger · 2020 to 2026
$2.9M
NIGMS NIH HHS T32 GM136572
6 · The paper itself

Abstract

Short-lived, radioactive lanthanides comprise an emerging class of radioisotopes attractive for biomedical imaging and therapy applications. To deliver such isotopes to target tissues, they must be appended to entities that target antigens overexpressed on the target cell's surface. However, the thermally sensitive nature of biomolecule-derived targeting vectors requires the incorporation of these isotopes without the use of denaturing temperatures or extreme pH conditions; chelating systems that can capture large radioisotopes under mild conditions are therefore highly desirable. Herein, we demonstrate the successful radiolabeling of the lanthanide-binding protein, lanmodulin (LanM), with medicinally relevant radioisotopes:

Identifiers

PMID37292057
PMCPMC10246553
OpenAlexW4366572588

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.