Evidence map›Paper›PMID 37291581›Full record

ArticleJournal of translational medicine2023

The relevance of pacing strategies in managing symptoms of post-COVID-19 syndrome.

Alaa Ghali, Valentin Lacombe, Camille Ravaiau, Estelle Delattre, Maria Ghali, Geoffrey Urbanski, Christian Lavigne

Open access · goldAbstract read
In one paragraph

Article in Journal of translational medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed, 1 pooled it
14.9field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 1 synthesis or guideline pooled it, 67 citations in OpenAlex.

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  4. Personalised Health Behaviour Support Programme in Adults With Post-COVID Syndrome: A Randomised, Controlled Pilot Feasibility Trial.Health expectations : an international journal of public participation in health care and health policy · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Alaa GhaliDepartment of Internal Medicine and Clinical Immunology, Angers University Hospital, 4 Rue Larrey, 49000, Angers, France. alghali@chu-angers.fr.ORCID 0000-0003-2040-3387
Valentin LacombeDepartment of Internal Medicine and Clinical Immunology, Angers University Hospital, 4 Rue Larrey, 49000, Angers, France.
Camille RavaiauDepartment of Internal Medicine and Clinical Immunology, Angers University Hospital, 4 Rue Larrey, 49000, Angers, France.
Estelle DelattreDepartment of Internal Medicine and Clinical Immunology, Angers University Hospital, 4 Rue Larrey, 49000, Angers, France.
Maria GhaliDepartment of General Medicine, Faculty of Medicine of Angers, Angers, France.
Geoffrey UrbanskiDepartment of Internal Medicine and Clinical Immunology, Angers University Hospital, 4 Rue Larrey, 49000, Angers, France.
Christian LavigneDepartment of Internal Medicine and Clinical Immunology, Angers University Hospital, 4 Rue Larrey, 49000, Angers, France.
Centre Hospitalier Universitaire d'Angers · FRUniversité d'Angers · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPost-COVID-19 syndrome (PCS) shares many features with myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS). PCS represents a major health issue worldwide because it severely impacts patients' work activities and their quality of life. In the absence of treatment for both conditions and given the beneficial effect of pacing strategies in ME/CFS, we conducted this study to assess the effectiveness of pacing in PCS patients.

methodsWe retrospectively included patients meeting the World Health Organization definition of PCS who attended the Internal Medicine Department of Angers University Hospital, France between June 2020 and June 2022, and were followed up until December 2022. Pacing strategies were systematically proposed for all patients. Their medical records were reviewed and data related to baseline and follow-up assessments were collected. This included epidemiological characteristics, COVID-19 symptoms and associated conditions, fatigue features, perceived health status, employment activity, and the degree of pacing adherence assessed by the engagement in pacing subscale (EPS). Recovery was defined as the ability to return to work, and improvement was regarded as the reduction of the number and severity of symptoms.

resultsA total of 86 patients were included and followed-up for a median time of 10 [6-13] months. Recovery and improvement rates were 33.7% and 23.3%, respectively. The EPS score was the only variable significantly associated with recovery on multivariate analysis (OR 40.43 [95% CI 6.22-262.6], p < 0.001). Patients who better adhered to pacing (high EPS scores) experienced significantly higher recovery and improvement rates (60-33.3% respectively) than those with low (5.5-5.5% respectively), or moderate (4.3-17.4% respectively) scores.

conclusionOur findings demonstrated that pacing is effective in the management of patients with PCS, and that high levels of adherence to pacing are associated with better outcomes.

Indexed as

COVID-19Fatigue Syndrome, ChronicHumansPost-Acute COVID-19 SyndromeQuality of LifeRetrospective StudiesAdherenceMyalgic encephalomyelitis/chronic fatigue syndromeOutcomesPacing strategiesPost-COVID syndrome

Identifiers

PMID37291581
PMCPMC10248991
OpenAlexW4379967608

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.