Evidence map›Paper›PMID 37291501›Full record

ArticleBMC neurology2023

Microwave ablation combined with vertebral augmentation under real-time temperature monitoring for the treatment of painful spinal osteogenic metastases.

Jing Fan, Xusheng Zhang, Peishun Li, Linlin Wu, Qianqian Yuan, Yunling Bai, Sen Yang, Yuanyuan Qiu, Kaixian Zhang

Open access · goldAbstract read
In one paragraph

Article in BMC neurology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it, 5 citations in OpenAlex.

  1. Pooled it
  2. The safety and efficacy of combined microwave ablation and percutaneous vertebral augmentation for spinal metastasis: a systematic review and meta-analysis of evidence in the last 6 years.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026
    Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Jing FanDepartment of Oncology, Tengzhou Central People's Hospital, Affiliated to Jining Medical College, Tengzhou, China.
Xusheng ZhangDepartment of Oncology, Tengzhou Central People's Hospital, Affiliated to Jining Medical College, Tengzhou, China.
Peishun LiDepartment of Oncology, Tengzhou Central People's Hospital, Affiliated to Jining Medical College, Tengzhou, China.
Linlin WuDepartment of Oncology, Tengzhou Central People's Hospital, Affiliated to Jining Medical College, Tengzhou, China.
Qianqian YuanDepartment of Oncology, Tengzhou Central People's Hospital, Affiliated to Jining Medical College, Tengzhou, China.
Yunling BaiDepartment of Oncology, Tengzhou Central People's Hospital, Affiliated to Jining Medical College, Tengzhou, China.
Sen YangDepartment of Oncology, Tengzhou Central People's Hospital, Affiliated to Jining Medical College, Tengzhou, China.
Yuanyuan QiuDepartment of Oncology, Tengzhou Central People's Hospital, Affiliated to Jining Medical College, Tengzhou, China.
Kaixian ZhangDepartment of Oncology, Tengzhou Central People's Hospital, Affiliated to Jining Medical College, Tengzhou, China. kaixianzhangtz@163.com.
Tengzhou Central People's Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo evaluate the safety and efficacy of computed tomography (CT)-guided microwave ablation combined with vertebral augmentation under real-time temperature monitoring in the treatment of painful osteogenic spinal metastases.

methodsThis retrospective study included 38 patients with 63 osteogenic metastatic spinal lesions treated using CT-guided microwave ablation and vertebral augmentation under real-time temperature monitoring. Visual analog scale scores, daily morphine consumption, and Oswestry Disability Index scores were used to evaluate efficacy of the treatment.

resultsMicrowave ablation combined with vertebral augmentation reduced the mean visual analog scale scores from 6.40 ± 1.90 preoperatively to 3.32 ± 0.96 at 24 h, 2.24 ± 0.91 at 1 week, 1.92 ± 1.32 at 4 weeks, 1.79 ± 1.45 at 12 weeks, and 1.39 ± 1.12 at 24 weeks postoperatively (all p < 0.001). The mean preoperative daily morphine consumption was 108.95 ± 56.41 mg, which decreased to 50.13 ± 25.46 mg at 24 h, 31.18 ± 18.58 mg at 1 week, 22.50 ± 16.63 mg at 4 weeks, 21.71 ± 17.68 mg at 12 weeks, and 17.27 ± 16.82 mg at 24 weeks postoperatively (all p < 0.001). During the follow-up period, the Oswestry Disability Index scores significantly reduced (p < 0.001). Bone cement leakage occurred in 25 vertebral bodies, with an incidence of 39.7% (25/63).

conclusionsThe results indicate that microwave ablation combined with vertebral augmentation under real-time temperature monitoring is a feasible, effective, and safe treatment for painful osteoblast spinal metastases.

Indexed as

Spinal FracturesSpinal NeoplasmsHumansMicrowavesMorphinePainPain MeasurementRetrospective StudiesTemperatureTreatment OutcomeMorphineMicrowave ablationOsteoblastic metastasisReal-time temperature monitoringRefractory painVertebral augmentation

Identifiers

PMID37291501
PMCPMC10249312
OpenAlexW4379966738

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.