SynthesisBMC cancer2023
Log odds of positive lymph nodes as a novel prognostic predictor for gastric cancer: a systematic review and meta-analysis.
Synthesis in BMC cancer, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed, 13 citations in OpenAlex.
- Intratumoral heterogeneity of intermediate CLDN18.2 expression in gastric cancer.International journal of clinical oncology · 2026Article
- The clinical relevance of LODDS for post-mastectomy radiotherapy in T1-2N1M0 breast cancer: a real-world propensity score-weighted analysis using the SEER database.Gland surgery · 2026Article
- Prognostic impact of lymph node ratio after suboptimal lymphadenectomy in gastric cancer: a retrospective cohort study with interaction analysis.World journal of surgical oncology · 2026Article
- The prognostic value of log odds of positive lymph nodes in patients with resectable locally advanced gastric cancer following neoadjuvant therapy: results from the SEER database.Translational cancer research · 2026Article
- N-LODDS: A Novel Integrated Lymph Node Staging System Enhancing Prognostic Accuracy in Non-Small-Cell Lung Cancer.Annals of surgical oncology · 2026Article
- Completion of perioperative chemotherapy and tumor regression grade as independent predictors of one-year survival after total gastrectomy for gastric cancer: a retrospective cohort study.World journal of surgical oncology · 2026Article
- Sentinel lymph node detection in gastric cancer using a dual tracer (Superparamagnetic iron oxide and methylene blue): a prospective study with histological and OSNA validation.Scientific reports · 2026Article
- Optimizing gastric cancer treatment: the role of LODDs in lymph node staging.Frontiers in oncology · 2026Article
- Perioperative CALLY dynamics after curative gastrectomy for gastric adenocarcinoma: associations with nodal tumor burden, textbook surgical outcome, and disease-free survival.Frontiers in oncology · 2026Article
- Integrating image processing with deep convolutional neural networks for gene selection and cancer classification using microarray data.Scientific reports · 2025Article
- Historical evolution and current research status of lymph node staging in gastric cancer: a review.World journal of surgical oncology · 2025Review
- Evaluating log odds of positive lymph nodes as a prognostic tool in differentiated gastric cancer: A retrospective study.World journal of gastroenterology · 2025Article
- Evaluation of LNR and modified N stage systems for prognostic stratification of metastatic lymph nodes in stage III colorectal Cancer.Scientific reports · 2025Article
- Evaluation of three lymph node staging systems for prognostic prediction in gastric cancer: A systematic review and meta-analysis.World journal of gastrointestinal oncology · 2025Article
- Machine learning models based on log odds of positive lymph nodes for predicting survival in TFrontiers in oncology · 2025Article
- Analysis of the predictive postoperative recurrence performance of three lymph node staging systems in patients with colon cancer.Frontiers in oncology · 2025Article
- Comparison of the predictive performance of three lymph node staging systems for late-onset gastric cancer patients after surgery.Frontiers in surgery · 2024Article
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16 authors at 4 institutions in 1 country.
Funding
Abstract
backgroundWe conducted a systematic review and meta-analysis to summarize the predictive and prognostic ability of the log odds of positive lymph nodes (LODDS) staging system and compare it with pathological N (pN) classification and the ratio-based lymph node system (rN) for the overall survival (OS) of gastric cancer (GC).
methodsThrough a systematic review till March 7, 2022, we identified population-based studies that reported the prognostic effects of LODDS in patients with GC. We compare the predictive effectiveness of the LODDS staging system with that of the rN and pN classification systems for the OS of GC.
resultsTwelve studies comprising 20,312 patients were included in this systematic review and meta-analysis. The results showed that LODDS1, LODDS2, LODDS3, and LODDS4 in GC patients were correlated with poor OS compared with LODDS0 (LODDS1 vs. LODDS0: HR = 1.62, 95% CI (1.42, 1.85); LODDS2 vs. LODDS0: HR = 2.47, 95% CI (2.02, 3.03); LODDS3 vs. LODDS0: HR = 3.15, 95% CI (2.50, 3.97); LODDS4 vs. LODDS0: HR = 4.55, 95% CI (3.29, 6.29)). Additionally, significant differences in survival were observed among patients with different LODDS classifications (all P-values were < 0.001) with the same rN and pN classifications. Meanwhile, for patients with different pN or rN classifications with the same LODDS classification, prognosis was highly similar.
conclusionThe findings show that LODDS is correlated with the prognosis of GC patients and is superior to the pN and rN classifications for prognostic assessment.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.