ArticleHormones (Athens, Greece)2023
Hmrbase2: a comprehensive database of hormones and their receptors.
Article in Hormones (Athens, Greece), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed, 9 citations in OpenAlex.
- The total mass, copy number, and distribution of hormones in the human bloodstream.PLoS biology · 2026Article
- HORDB 2.0: a comprehensive dataset of peptide hormones.Scientific data · 2026Article
- MitoCommun: a database for decoding mitochondrial communication networks.BMC genomics · 2026Article
- Bioinformatics approaches for studying molecular sex differences in complex diseases.Briefings in bioinformatics · 2024Review
- Studies on transgender medicine, exploring databases, and more on metabolic syndrome and diabetes.Hormones (Athens, Greece) · 2023Article
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
purposeHormones play a critical role in regulating various physiological processes and any hormonal imbalances can lead to major endocrine disorders. Thus, studying hormones is essential for both the therapeutics and the diagnostics of hormonal diseases. To facilitate this need, we have developed Hmrbase2, a comprehensive platform that provides extensive information on hormones.
methodsHmrbase2 is a web-based database which is an update of a previously published database, Hmrbase ( http://crdd.osdd.net/raghava/hmrbase/ ). We collected a large amount of information on peptide and non-peptide hormones and hormone receptors, this information being sourced from Hmrbase, HMDB, UniProt, HORDB, ENDONET, PubChem, and the medical literature.
resultsHmrbase2 contains a total of 12,056 entries, which is more than twice the number of entries contained in the previous version Hmrbase. These include 7406, 753, and 3897 entries for peptide hormones, non-peptide hormones, and hormone receptors, respectively, from 803 organisms compared to the 562 organisms in the previous version. The database also hosts 5662 hormone receptor pairs. The source organism, function, and subcellular location are provided for peptide hormones and receptors and properties such as melting point and water solubility is provided for non-peptide hormones. Besides browsing and keyword search, an advanced search option has also been supplied. Additionally, a similarity search module has been incorporated enabling users to run similarity searches against peptide hormone sequences using BLAST and Smith-Waterman.
conclusionsTo make the database accessible to various users, we designed a user-friendly, responsive website that can be easily used on smartphones, tablets, and desktop computers. The updated database version, Hmrbase2, offers improved data content compared to the previous version. Hmrbase2 is freely available at https://webs.iiitd.edu.in/raghava/hmrbase2 .
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.