Evidence map›Paper›PMID 37291067›Full record

ArticleThe American journal on addictions2023

Medical marijuana access and prolonged opioid use among adolescents and young adults.

Kyungha Kim, Rosalie L Pacula, Andrew W Dick, Bradley D Stein, Benjamin G Druss, Edeanya Agbese, Austin C Cohrs, Douglas L Leslie

Open access · hybridAbstract read
In one paragraph

Article in The American journal on addictions, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Kyungha KimDepartment of Public Health Sciences, Penn State College of Medicine, Hershey, Pennsylvania, USA.ORCID 0000-0001-7382-6733
Rosalie L PaculaSol Price School of Public Policy, Schaeffer Center for Health Policy & Economics, University of Southern California, Los Angeles, California, USA.
Andrew W DickRAND Corporation, Boston, Massachusetts, USA.
Bradley D SteinRAND Corporation, Pittsburgh, Pennsylvania, USA.
Benjamin G DrussRollins School of Public Health, Emory University, Atlanta, Georgia, USA.
Edeanya AgbeseDepartment of Public Health Sciences, Penn State College of Medicine, Hershey, Pennsylvania, USA.
Austin C CohrsDepartment of Public Health Sciences, Penn State College of Medicine, Hershey, Pennsylvania, USA.
Douglas L LeslieDepartment of Public Health Sciences, Penn State College of Medicine, Hershey, Pennsylvania, USA.
Pennsylvania State University · USRAND Corporation · USEmory University · USUniversity of Southern California · US

Funding

Opioid use disorders in adolescents: predictors of treatment and outcomesR01DA047396 · NIDA · PENNSYLVANIA STATE UNIV HERSHEY MED CTR · PI LESLIE, DOUGLAS L. · 2019 to 2021
$1.9M
NIDA NIH HHS R01 DA047396NIDA NIH HHS R01DA047396
6 · The paper itself

Abstract

BACKGROUND AND

objectivesLaws liberalizing access to medical marijuana are associated with reduced opioid analgesic use among adults, but little is known about the impact of such policies on adolescents and young adults.

methodsThis retrospective cohort study used 2005 to 2014 claims from MarketScan® Commercial database, which covers all 50 states and Washington D.C. The sample included 195,204 adolescent and young adult patients (aged 12-25) who underwent one of 13 surgical procedures.

resultsOf the 195,204 patients, 4.8% had prolonged opioid use. Several factors were associated with a higher likelihood of prolonged opioid use, including being female (adjusted odds ratio [aOR], 1.27; 95% confidence interval [CI], 1.21-1.33), longer hospital stay (aOR, 1.04; 95% CI, 1.02-1.06), greater days of index opioid supply (8-14 days: aOR, 1.39, 95% CI, 1.33-1.45; greater than 14 days: aOR, 2.42, 95% CI, 2.26-2.59), rural residence (aOR, 1.07; 95% CI, 1.01-1.14), and cholecystectomy (aOR, 1.16; 95% CI, 1.08-1.25). There was not a significant association of medical marijuana dispensary laws on prolonged opioid use (aOR, 0.98; 95% CI, 0.81-1.18). CONCLUSIONS AND SCIENTIFIC SIGNIFICANCE: Medical marijuana has been suggested as a substitute for opioids, but our results focusing on adolescents and young adults provide new evidence that this particularly vulnerable population does not exhibit reductions in prolonged use of opioids after surgery when they have legal access to medical marijuana. These findings are the first to demonstrate potentially important age differences in sustained use of opioids, and point to the need for prescriber oversight and management with this vulnerable population.

Indexed as

CannabisMedical MarijuanaOpioid-Related DisordersAdolescentAnalgesics, OpioidFemaleHumansMaleRetrospective StudiesUnited StatesYoung AdultAnalgesics, OpioidMedical Marijuana

Identifiers

PMID37291067
PMCPMC10686234
OpenAlexW4379928327

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.