ArticleCurrent biology : CB2023
The origin and evolution of sex chromosomes, revealed by sequencing of the Silene latifolia female genome.
Article in Current biology : CB, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
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25 citing papers in PubMed, 39 citations in OpenAlex.
- Incomplete climate-driven peripatric speciation in Moehringia sect. Moehringia (Caryophyllaceae) in the European Alps.American journal of botany · 2026Article
- Sexual antagonism, mating systems, and recombination suppression on sex chromosomes.Evolution letters · 2026Article
- Developmental robustness of the shoot apical meristem despite sex-chromosome dosage imbalance in Silene latifolia.BMC plant biology · 2026Article
- Silene, a versatile model system: from sex and genome evolution to ecology and speciation.The New phytologist · 2026Review
- A haplotype-resolved nutmeg genome reveals XY sex chromosome evolution and enables molecular sexing.Communications biology · 2026Article
- Whole-genome sequencing reveals a possible molecular basis of sex determination in the dioecious wild yam Dioscorea tokoro.PLoS genetics · 2026Article
- High-quality genome assembly and linkage map for a rapidly evolving plant species: Silene uniflora.G3 (Bethesda, Md.) · 2026Article
- Recreating viable YYNature communications · 2026Article
- Chromosome-level genome assembly of the traditional Chinese medical plant Pseudostellaria heterophylla.Scientific data · 2025Article
- Structural and evolutionary features of red algal UV sex chromosomes.Genome biology · 2025Article
- EASYstrata: an all-in-one workflow for genome annotation and genomic divergence analysis.NAR genomics and bioinformatics · 2025Article
- Evolution and functioning of an X-A balance sex-determining system in hops.Nature plants · 2025Article
- Genetic Isolation among Four Lineages of Silene nutans.Plant & cell physiology · 2025Article
- The fourspine stickleback (Apeltes quadracus) has an XY sex chromosome system with polymorphic inversions on both X and Y chromosomes.PLoS genetics · 2025Article
- TheScience (New York, N.Y.) · 2025Article
- The genome of Hippophae salicifolia provides new insights into the sexual differentiation of sea buckthorn.GigaScience · 2025Article
- 3D chromatin maps of a brown alga reveal U/V sex chromosome spatial organization.Nature communications · 2024Article
- Sex chromosome cycle as a mechanism of stable sex determination.Journal of biochemistry · 2024Review
- Why should we study plant sex chromosomes?The Plant cell · 2024Review
- Evolution of a plant sex chromosome driven by expanding pericentromeric recombination suppression.Scientific reports · 2024Article
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Authors and funding
10 authors at 5 institutions in 4 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
White campion (Silene latifolia, Caryophyllaceae) was the first vascular plant where sex chromosomes were discovered. This species is a classic model for studies on plant sex chromosomes due to presence of large, clearly distinguishable X and Y chromosomes that originated de novo about 11 million years ago (mya), but lack of genomic resources for this relatively large genome (∼2.8 Gb) remains a significant hurdle. Here we report S. latifolia female genome assembly integrated with sex-specific genetic maps of this species, focusing on sex chromosomes and their evolution. The analysis reveals a highly heterogeneous recombination landscape with strong reduction in recombination rate in the central parts of all chromosomes. Recombination on the X chromosome in female meiosis primarily occurs at the very ends, and over 85% of the X chromosome length is located in a massive (∼330 Mb) gene-poor, rarely recombining pericentromeric region (Xpr). The results indicate that the non-recombining region on the Y chromosome (NRY) initially evolved in a relatively small (∼15 Mb), actively recombining region at the end of the q-arm, possibly as a result of inversion on the nascent X chromosome. The NRY expanded about 6 mya via linkage between the Xpr and the sex-determining region, which may have been caused by expanding pericentromeric recombination suppression on the X chromosome. These findings shed light on the origin of sex chromosomes in S. latifolia and yield genomic resources to assist ongoing and future investigations into sex chromosome evolution.
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